Lyptomet Tablet
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Sitagliptin (50mg) + Metformin (1000mg)
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Sitagliptin inhibits DPP-4, increasing incretin levels, which stimulate insulin release and reduce glucagon secretion.
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Medical applications
Lyptomet Tablet contains a combination of Sitagliptin 50 mg and Metformin 1000 mg, formulated for the management of type 2 diabetes mellitus. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that enhances the levels of incretin hormones, thereby increasing insulin release and decreasing glucagon secretion in a glucose-dependent manner. Metformin, a biguanide, primarily acts by reducing hepatic glucose production, improving insulin sensitivity, and enhancing peripheral glucose uptake.
The synergistic action of these two agents helps achieve better glycemic control in patients inadequately controlled by diet, exercise, and monotherapy. Lyptomet is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. It may be used as initial therapy in patients likely to benefit from dual therapy or as an add-on to other antidiabetic agents.
The combination is generally well-tolerated; however, common adverse effects may include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal discomfort, primarily due to metformin. Caution is advised in patients with renal impairment, hepatic dysfunction, or conditions predisposing to hypoxia. Regular monitoring of blood glucose and renal function is recommended during therapy.
Lyptomet should be used under medical supervision with appropriate lifestyle modifications for optimal efficacy.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Information regarding the use of Lyptomet Tablet during pregnancy is not available. Please consult your doctor.
High Risk
Lyptomet Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Lyptomet Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lyptomet Tablet may be needed. Please consult your doctor. Use of Lyptomet Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Exercise Caution
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Consult Doctor
Lyptomet Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
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