
Gliclazide (40mg) + Metformin (500mg)
Active composition
+1 more active ingredient
Gliclazide stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues.
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Medical applications
Loyzide M 40mg/500mg Tablet is a combination oral antidiabetic medication containing Gliclazide 40mg and Metformin 500mg, indicated for the management of type 2 diabetes mellitus. Gliclazide, a sulfonylurea class agent, functions by stimulating pancreatic beta cells to enhance insulin secretion, thereby improving glycemic control. Metformin, a biguanide, primarily acts by decreasing hepatic glucose production and improving peripheral insulin sensitivity. The synergistic action of these agents helps achieve better blood glucose regulation in patients inadequately controlled by diet and exercise alone. Loyzide M is typically prescribed when monotherapy with either agent is insufficient. It is important to initiate therapy with caution, considering patient-specific factors such as renal function, hepatic status, and risk of hypoglycemia. Common adverse effects may include gastrointestinal disturbances, hypoglycemia, and rarely, lactic acidosis associated with Metformin. Regular monitoring of blood glucose levels, renal function, and periodic assessment of liver enzymes is recommended during treatment. Patients should be advised to adhere to dietary and lifestyle modifications alongside medication use. Loyzide M 40mg/500mg Tablet should be used under medical supervision, with dose adjustments tailored to individual therapeutic response and tolerability.
How to use Loyzide M Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Loyzide M 40mg/500mg Tablet is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Loyzide M 40mg/500mg Tablet.
High Risk
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Loyzide M 40mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Loyzide M 40mg/500mg Tablet may be needed. Please consult your doctor. Loyzide M 40mg/500mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
Regular Checkup
Loyzide M 40mg/500mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consult Doctor
Loyzide M 40mg/500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Loyzide M 40mg/500mg Tablet may be needed. Please consult your doctor. Use of Loyzide M 40mg/500mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Regular Checkup
0 reviews for Loyzide M 40mg/500mg Tablet

Gliclazide (40mg) + Metformin (500mg)
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Active composition
+1 more active ingredient
Gliclazide stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues.
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Medical applications
Loyzide M 40mg/500mg Tablet is a combination oral antidiabetic medication containing Gliclazide 40mg and Metformin 500mg, indicated for the management of type 2 diabetes mellitus. Gliclazide, a sulfonylurea class agent, functions by stimulating pancreatic beta cells to enhance insulin secretion, thereby improving glycemic control. Metformin, a biguanide, primarily acts by decreasing hepatic glucose production and improving peripheral insulin sensitivity. The synergistic action of these agents helps achieve better blood glucose regulation in patients inadequately controlled by diet and exercise alone. Loyzide M is typically prescribed when monotherapy with either agent is insufficient. It is important to initiate therapy with caution, considering patient-specific factors such as renal function, hepatic status, and risk of hypoglycemia. Common adverse effects may include gastrointestinal disturbances, hypoglycemia, and rarely, lactic acidosis associated with Metformin. Regular monitoring of blood glucose levels, renal function, and periodic assessment of liver enzymes is recommended during treatment. Patients should be advised to adhere to dietary and lifestyle modifications alongside medication use. Loyzide M 40mg/500mg Tablet should be used under medical supervision, with dose adjustments tailored to individual therapeutic response and tolerability.
How to use Loyzide M Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Loyzide M 40mg/500mg Tablet is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Loyzide M 40mg/500mg Tablet.
High Risk
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Loyzide M 40mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Loyzide M 40mg/500mg Tablet may be needed. Please consult your doctor. Loyzide M 40mg/500mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
Regular Checkup
Loyzide M 40mg/500mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consult Doctor
Loyzide M 40mg/500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Loyzide M 40mg/500mg Tablet may be needed. Please consult your doctor. Use of Loyzide M 40mg/500mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Regular Checkup
0 reviews for Loyzide M 40mg/500mg Tablet













