
Loteprednol etabonate (5mg) + Gatifloxacin (3mg)
Active composition
+1 more active ingredient
Loteprednol Etabonate inhibits the release of inflammatory mediators, reducing eye inflammation and pain.
Gatifloxacin inhibits DNA gyrase and topoisomerase IV, preventing bacterial DNA replication and transcription, leading to bacterial cell death.
Medical applications
Lotegate Eye Drop is a combination ophthalmic solution containing Gatifloxacin 3 mg and Loteprednol etabonate 5 mg, formulated for the treatment of bacterial ocular infections accompanied by inflammation. Gatifloxacin, a fourth-generation fluoroquinolone antibiotic, exhibits broad-spectrum bactericidal activity by inhibiting bacterial DNA gyrase and topoisomerase IV, thereby preventing bacterial replication and promoting rapid eradication of susceptible pathogens. Loteprednol etabonate, a corticosteroid with potent anti-inflammatory properties, acts by modulating the inflammatory response through inhibition of multiple inflammatory mediators, reducing ocular redness, swelling, and discomfort. This dual-action formulation is indicated for bacterial conjunctivitis, keratitis, and other ocular surface infections where inflammation is present. Lotegate Eye Drop should be administered as directed by a healthcare professional, typically instilled into the affected eye(s) multiple times daily for the prescribed duration. Caution is advised in patients with known hypersensitivity to fluoroquinolones or corticosteroids, and prolonged use should be monitored to prevent potential adverse effects such as increased intraocular pressure or secondary infections. This combination therapy offers an effective approach to managing infectious ocular conditions while simultaneously controlling associated inflammatory symptoms, promoting faster recovery and improved patient comfort.
How to use Lotegate Eye Drop This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off the extra liquid.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
No interaction found/established
High Risk
Lotegate Eye Drop may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.
Exercise Caution
No interaction found/established
Regular Checkup
Information regarding the use of Lotegate Eye Drop during pregnancy is not available. Please consult your doctor.
Consult Doctor
No interaction found/established
Regular Checkup
0 reviews for Lotegate Eye Drop

Gatifloxacin (3mg) + Loteprednol etabonate (5mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Loteprednol Etabonate inhibits the release of inflammatory mediators, reducing eye inflammation and pain.
Gatifloxacin inhibits DNA gyrase and topoisomerase IV, preventing bacterial DNA replication and transcription, leading to bacterial cell death.
Medical applications
Lotegate Eye Drop is a combination ophthalmic solution containing Gatifloxacin 3 mg and Loteprednol etabonate 5 mg, formulated for the treatment of bacterial ocular infections accompanied by inflammation. Gatifloxacin, a fourth-generation fluoroquinolone antibiotic, exhibits broad-spectrum bactericidal activity by inhibiting bacterial DNA gyrase and topoisomerase IV, thereby preventing bacterial replication and promoting rapid eradication of susceptible pathogens. Loteprednol etabonate, a corticosteroid with potent anti-inflammatory properties, acts by modulating the inflammatory response through inhibition of multiple inflammatory mediators, reducing ocular redness, swelling, and discomfort. This dual-action formulation is indicated for bacterial conjunctivitis, keratitis, and other ocular surface infections where inflammation is present. Lotegate Eye Drop should be administered as directed by a healthcare professional, typically instilled into the affected eye(s) multiple times daily for the prescribed duration. Caution is advised in patients with known hypersensitivity to fluoroquinolones or corticosteroids, and prolonged use should be monitored to prevent potential adverse effects such as increased intraocular pressure or secondary infections. This combination therapy offers an effective approach to managing infectious ocular conditions while simultaneously controlling associated inflammatory symptoms, promoting faster recovery and improved patient comfort.
How to use Lotegate Eye Drop This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off the extra liquid.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
No interaction found/established
High Risk
Lotegate Eye Drop may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.
Exercise Caution
No interaction found/established
Regular Checkup
Information regarding the use of Lotegate Eye Drop during pregnancy is not available. Please consult your doctor.
Consult Doctor
No interaction found/established
Regular Checkup
0 reviews for Lotegate Eye Drop















