
Serratiopeptidase (15mg) + Aceclofenac (100mg) + Paracetamol (325mg)
Active composition
+2 more active ingredients
Serratiopeptidase acts as a proteolytic enzyme, breaking down fibrin and other proteins involved in inflammation, thereby reducing pain and swelling.
Aceclofenac inhibits COX-1 and COX-2 enzymes, leading to decreased synthesis of prostaglandins, which are responsible for pain and inflammation.
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Medical applications
Lofidol-SP Tablet is a combination analgesic formulation containing Aceclofenac 100 mg, Paracetamol 325 mg, and Serratiopeptidase 15 mg, designed to provide effective relief from pain and inflammation. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), exerts its action by inhibiting cyclooxygenase enzymes, thereby reducing prostaglandin synthesis, which leads to decreased inflammation and pain. Paracetamol acts centrally to alleviate pain and reduce fever through inhibition of prostaglandin synthesis in the central nervous system. Serratiopeptidase, a proteolytic enzyme, facilitates the breakdown of inflammatory mediators and promotes the resolution of edema and swelling by enhancing fibrinolytic activity. The synergistic effect of these three components makes Lofidol-SP effective in managing musculoskeletal disorders such as osteoarthritis, rheumatoid arthritis, and soft tissue injuries including sprains and strains. It is also beneficial in postoperative pain and inflammatory conditions. The combination ensures rapid onset of analgesia with sustained anti-inflammatory benefits while minimizing gastrointestinal side effects commonly associated with NSAIDs alone. Lofidol-SP should be used under medical supervision, with caution in patients with a history of gastrointestinal ulcers, bleeding disorders, or hepatic impairment. Regular monitoring is advised during prolonged therapy.
How to use Lofidol-SP Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lofidol-SP Tablet is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Lofidol-SP Tablet.
High Risk
Lofidol-SP Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Lofidol-SP Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Lofidol-SP Tablet should be used with caution in patients with liver disease. Dose adjustment of Lofidol-SP Tablet may be needed. Please consult your doctor. However, the use of Lofidol-SP Tablet is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
Information regarding the use of Lofidol-SP Tablet during breastfeeding is not available. Please consult your doctor.
Consult Doctor
Lofidol-SP Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lofidol-SP Tablet may be needed. Please consult your doctor. Use of Lofidol-SP Tablet is not recommended in patients with severe kidney disease.
Regular Checkup
0 reviews for Lofidol-SP Tablet

Aceclofenac (100mg) + Paracetamol (325mg) + Serratiopeptidase (15mg)
Cheaper alternative availability
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Active composition
+2 more active ingredients
Serratiopeptidase acts as a proteolytic enzyme, breaking down fibrin and other proteins involved in inflammation, thereby reducing pain and swelling.
Aceclofenac inhibits COX-1 and COX-2 enzymes, leading to decreased synthesis of prostaglandins, which are responsible for pain and inflammation.
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Medical applications
Lofidol-SP Tablet is a combination analgesic formulation containing Aceclofenac 100 mg, Paracetamol 325 mg, and Serratiopeptidase 15 mg, designed to provide effective relief from pain and inflammation. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), exerts its action by inhibiting cyclooxygenase enzymes, thereby reducing prostaglandin synthesis, which leads to decreased inflammation and pain. Paracetamol acts centrally to alleviate pain and reduce fever through inhibition of prostaglandin synthesis in the central nervous system. Serratiopeptidase, a proteolytic enzyme, facilitates the breakdown of inflammatory mediators and promotes the resolution of edema and swelling by enhancing fibrinolytic activity. The synergistic effect of these three components makes Lofidol-SP effective in managing musculoskeletal disorders such as osteoarthritis, rheumatoid arthritis, and soft tissue injuries including sprains and strains. It is also beneficial in postoperative pain and inflammatory conditions. The combination ensures rapid onset of analgesia with sustained anti-inflammatory benefits while minimizing gastrointestinal side effects commonly associated with NSAIDs alone. Lofidol-SP should be used under medical supervision, with caution in patients with a history of gastrointestinal ulcers, bleeding disorders, or hepatic impairment. Regular monitoring is advised during prolonged therapy.
How to use Lofidol-SP Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lofidol-SP Tablet is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Lofidol-SP Tablet.
High Risk
Lofidol-SP Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Lofidol-SP Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Lofidol-SP Tablet should be used with caution in patients with liver disease. Dose adjustment of Lofidol-SP Tablet may be needed. Please consult your doctor. However, the use of Lofidol-SP Tablet is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
Information regarding the use of Lofidol-SP Tablet during breastfeeding is not available. Please consult your doctor.
Consult Doctor
Lofidol-SP Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lofidol-SP Tablet may be needed. Please consult your doctor. Use of Lofidol-SP Tablet is not recommended in patients with severe kidney disease.
Regular Checkup
0 reviews for Lofidol-SP Tablet











