
Leflunomide (10mg)
Active composition
Leflunomide inhibits dihydroorotate dehydrogenase, reducing the proliferation of activated lymphocytes and thus decreasing inflammation.
Medical applications
Lefra 10 Tablet contains Leflunomide 10 mg, an immunomodulatory agent primarily indicated for the treatment of active rheumatoid arthritis and psoriatic arthritis. Leflunomide acts by inhibiting dihydroorotate dehydrogenase, a key enzyme involved in pyrimidine synthesis, thereby reducing the proliferation of activated lymphocytes responsible for the inflammatory process. This mechanism helps in decreasing joint inflammation, pain, and structural damage associated with autoimmune conditions. Lefra 10 is typically prescribed as part of a disease-modifying antirheumatic drug (DMARD) regimen to improve physical function and slow disease progression. The tablet should be administered orally, with or without food, as directed by a healthcare professional. It is essential to monitor liver function tests and blood counts periodically during therapy due to potential hepatotoxicity and hematological adverse effects. Lefra 10 is contraindicated in patients with severe hepatic impairment, pregnancy, or hypersensitivity to Leflunomide. Patients should be advised regarding potential side effects such as diarrhea, rash, alopecia, and elevated liver enzymes. Concomitant use with other immunosuppressants requires caution. Proper patient selection and monitoring can optimize therapeutic outcomes while minimizing risks associated with Lefra 10 Tablet.
How to use Lefra Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lefra 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Lefra 10 Tablet.
High Risk
Lefra 10 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Medical Advice
Lefra 10 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Lefra 10 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
Lefra 10 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Lefra 10 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lefra 10 Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Lefra 10 Tablet

Leflunomide (10mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
Leflunomide inhibits dihydroorotate dehydrogenase, reducing the proliferation of activated lymphocytes and thus decreasing inflammation.
Medical applications
Lefra 10 Tablet contains Leflunomide 10 mg, an immunomodulatory agent primarily indicated for the treatment of active rheumatoid arthritis and psoriatic arthritis. Leflunomide acts by inhibiting dihydroorotate dehydrogenase, a key enzyme involved in pyrimidine synthesis, thereby reducing the proliferation of activated lymphocytes responsible for the inflammatory process. This mechanism helps in decreasing joint inflammation, pain, and structural damage associated with autoimmune conditions. Lefra 10 is typically prescribed as part of a disease-modifying antirheumatic drug (DMARD) regimen to improve physical function and slow disease progression. The tablet should be administered orally, with or without food, as directed by a healthcare professional. It is essential to monitor liver function tests and blood counts periodically during therapy due to potential hepatotoxicity and hematological adverse effects. Lefra 10 is contraindicated in patients with severe hepatic impairment, pregnancy, or hypersensitivity to Leflunomide. Patients should be advised regarding potential side effects such as diarrhea, rash, alopecia, and elevated liver enzymes. Concomitant use with other immunosuppressants requires caution. Proper patient selection and monitoring can optimize therapeutic outcomes while minimizing risks associated with Lefra 10 Tablet.
How to use Lefra Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lefra 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Lefra 10 Tablet.
High Risk
Lefra 10 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Medical Advice
Lefra 10 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Lefra 10 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
Lefra 10 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Lefra 10 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lefra 10 Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Lefra 10 Tablet















