
Leflunomide (10mg)
Active composition
Leflunomide inhibits dihydroorotate dehydrogenase, reducing the proliferation of activated lymphocytes and thus decreasing inflammation.
Medical applications
Lefmaa 10 Tablet contains Leflunomide 10 mg, an immunomodulatory agent primarily indicated for the treatment of active rheumatoid arthritis and psoriatic arthritis. Leflunomide acts by inhibiting dihydroorotate dehydrogenase, a key enzyme involved in pyrimidine synthesis, thereby reducing the proliferation of activated lymphocytes responsible for inflammatory responses. This mechanism helps to alleviate joint inflammation, pain, and swelling, ultimately improving physical function and slowing disease progression. Lefmaa 10 is typically prescribed as part of a comprehensive treatment plan, which may include other disease-modifying antirheumatic drugs (DMARDs). The tablet should be administered orally, with or without food, as directed by a healthcare professional. Common adverse effects include gastrointestinal disturbances such as diarrhea, nausea, and abdominal pain, as well as elevated liver enzymes and potential hepatotoxicity, necessitating regular liver function monitoring during therapy. Patients should be advised regarding the risk of immunosuppression and the importance of reporting signs of infection promptly. Leflunomide is contraindicated in pregnancy due to teratogenicity and requires effective contraception during treatment and washout periods. Overall, Lefmaa 10 Tablet offers a valuable therapeutic option for managing autoimmune inflammatory conditions by modulating immune activity and improving patient quality of life.
How to use Lefmaa Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lefmaa 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Lefmaa 10 Tablet.
High Risk
Lefmaa 10 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Medical Advice
Lefmaa 10 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Lefmaa 10 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
Lefmaa 10 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Lefmaa 10 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lefmaa 10 Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Lefmaa 10 Tablet

Leflunomide (10mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
Leflunomide inhibits dihydroorotate dehydrogenase, reducing the proliferation of activated lymphocytes and thus decreasing inflammation.
Medical applications
Lefmaa 10 Tablet contains Leflunomide 10 mg, an immunomodulatory agent primarily indicated for the treatment of active rheumatoid arthritis and psoriatic arthritis. Leflunomide acts by inhibiting dihydroorotate dehydrogenase, a key enzyme involved in pyrimidine synthesis, thereby reducing the proliferation of activated lymphocytes responsible for inflammatory responses. This mechanism helps to alleviate joint inflammation, pain, and swelling, ultimately improving physical function and slowing disease progression. Lefmaa 10 is typically prescribed as part of a comprehensive treatment plan, which may include other disease-modifying antirheumatic drugs (DMARDs). The tablet should be administered orally, with or without food, as directed by a healthcare professional. Common adverse effects include gastrointestinal disturbances such as diarrhea, nausea, and abdominal pain, as well as elevated liver enzymes and potential hepatotoxicity, necessitating regular liver function monitoring during therapy. Patients should be advised regarding the risk of immunosuppression and the importance of reporting signs of infection promptly. Leflunomide is contraindicated in pregnancy due to teratogenicity and requires effective contraception during treatment and washout periods. Overall, Lefmaa 10 Tablet offers a valuable therapeutic option for managing autoimmune inflammatory conditions by modulating immune activity and improving patient quality of life.
How to use Lefmaa Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lefmaa 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Lefmaa 10 Tablet.
High Risk
Lefmaa 10 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Medical Advice
Lefmaa 10 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Lefmaa 10 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
Lefmaa 10 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Lefmaa 10 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lefmaa 10 Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Lefmaa 10 Tablet















