Kreztel-H 40 Tablet
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Telmisartan (40mg) + Hydrochlorothiazide (12.5mg)
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Hydrochlorothiazide inhibits sodium reabsorption in the distal convoluted tubule, leading to increased urine output and decreased blood volume.
Telmisartan selectively blocks angiotensin II receptors, leading to vasodilation and decreased blood pressure.
Medical applications
Kreztel-H 40 Tablet is a combination antihypertensive medication containing Telmisartan 40 mg and Hydrochlorothiazide 12.5 mg. Telmisartan is an angiotensin II receptor blocker (ARB) that selectively inhibits the binding of angiotensin II to the AT1 receptor, thereby preventing vasoconstriction and aldosterone secretion, which leads to vasodilation and reduction in blood pressure.
Hydrochlorothiazide is a thiazide diuretic that promotes diuresis by inhibiting sodium reabsorption in the distal convoluted tubules of the kidneys, resulting in decreased plasma volume and peripheral resistance. The synergistic action of these two agents effectively lowers elevated blood pressure in patients with essential hypertension, reducing the risk of cardiovascular events such as stroke and myocardial infarction.
Kreztel-H 40 is indicated for patients inadequately controlled on monotherapy or those who require combination therapy for optimal blood pressure management. It is important to monitor renal function, electrolytes, and blood pressure regularly during treatment. Caution is advised in patients with renal or hepatic impairment, electrolyte imbalances, or a history of hypersensitivity to sulfonamides.
Kreztel-H 40 should be used under medical supervision, with adherence to prescribed dosing to achieve desired therapeutic outcomes while minimizing adverse effects.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Kreztel-H 40 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Kreztel-H 40 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Kreztel-H 40 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Kreztel-H 40 Tablet may be needed. Please consult your doctor. Use of Kreztel-H 40 Tablet is not recommended in patients with severe kidney disease.
Exercise Caution
Kreztel-H 40 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Kreztel-H 40 Tablet should be used with caution in patients with liver disease. Dose adjustment of Kreztel-H 40 Tablet may be needed. Please consult your doctor.
Regular Checkup
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