Koxen-D 500 Tablet is a combination medication containing Naproxen 500 mg and Domperidone 10 mg, formulated to provide effective relief from pain and inflammation while minimizing gastrointestinal discomfort. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), exerts its therapeutic effect by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the synthesis of prostaglandins responsible for pain, inflammation, and fever. It is commonly indicated for conditions such as arthritis, musculoskeletal pain, dysmenorrhea, and other inflammatory disorders. Domperidone, a dopamine D2 receptor antagonist, enhances gastrointestinal motility and accelerates gastric emptying, which helps to counteract nausea, vomiting, and gastric stasis frequently associated with NSAID therapy. The combination of Naproxen and Domperidone in Koxen-D 500 Tablet allows for improved patient compliance by addressing both analgesic needs and gastrointestinal side effects. It is recommended to be taken under medical supervision, particularly in patients with a history of gastrointestinal ulcers, cardiovascular disease, or hepatic impairment. Common adverse effects may include gastrointestinal discomfort, headache, dizziness, and rarely, cardiac arrhythmias. Koxen-D 500 Tablet should be used at the prescribed dose and duration to ensure optimal efficacy and safety.

Dosage & How to Use

Dosage information not available. Please consult your doctor or pharmacist.