Kolibitor Solution for Infusion
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Vial of 5 ml • Liquid
Kolibitor Solution for Infusion
Sulfamethoxazole (80mg/ml) + Trimethoprim (16mg/ml)
₹390.00
Vial of 5 ml • Liquid
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Active composition
Sulfamethoxazole
+1 more active ingredient
How It Works
Trimethoprim inhibits dihydrofolate reductase, blocking folate synthesis and preventing bacterial growth.
All Active Ingredients
Sulfamethoxazole
Trimethoprim
Uses & Benefits
Medical applications
InfectionBacterialAntibiotic
Kolibitor Solution for Infusion contains a combination of Sulfamethoxazole (80 mg/ml) and Trimethoprim (16 mg/ml), which act synergistically as a potent antimicrobial agent. This formulation is indicated for the treatment of a variety of bacterial infections caused by susceptible strains, including urinary tract infections, respiratory tract infections, gastrointestinal infections, and certain types of systemic infections.
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Sulfamethoxazole, a sulfonamide antibiotic, inhibits bacterial synthesis of dihydrofolic acid, while Trimethoprim blocks the subsequent step of tetrahydrofolic acid formation, resulting in a sequential blockade of folic acid synthesis essential for bacterial growth and replication. Kolibitor Solution for Infusion is administered intravenously, allowing for rapid and effective delivery in patients unable to take oral medications or requiring high systemic concentrations.
Dosage and duration of therapy should be tailored according to the severity of infection, patient weight, renal function, and clinical response. Caution is advised in patients with hypersensitivity to sulfonamides or trimethoprim, as well as those with severe renal or hepatic impairment. Monitoring for adverse effects such as hypersensitivity reactions, hematological abnormalities, and renal function alterations is recommended during therapy.
This combination provides a broad-spectrum antibacterial effect, making it suitable for hospital use in managing serious infections.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Kolibitor Solution for Infusion is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Pregnancy
Kolibitor Solution for Infusion is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. There may be a possibility of skin rash in the baby.
Medical Advice
Driving
Kolibitor Solution for Infusion should be used with caution in patients with kidney disease. Dose adjustment of Kolibitor Solution for Infusion may be needed. Please consult your doctor. Use of Kolibitor Solution for Infusion is not recommended in patients with severe kidney disease.
Exercise Caution
Breastfeeding
It is not known whether Kolibitor Solution for Infusion alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Consult Doctor
Kidney
Kolibitor Solution for Infusion should be used with caution in patients with liver disease. Dose adjustment of Kolibitor Solution for Infusion may be needed. Please consult your doctor. Use of Kolibitor Solution for Infusion is not recommended in patients with the severe liver disease.
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