Ketoflox Ophthalmic Solution
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Ofloxacin (3mg/ml) + Ketorolac (5mg/ml)
1 units • Other
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Active composition
+1 more active ingredient
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Ketorolac inhibits cyclooxygenase enzymes, leading to decreased production of prostaglandins, which mediate pain and inflammation.
Medical applications
Ketoflox Ophthalmic Solution is a sterile ophthalmic formulation combining Ofloxacin 3 mg/ml, a broad-spectrum fluoroquinolone antibiotic, and Ketorolac 5 mg/ml, a nonsteroidal anti-inflammatory drug (NSAID). This dual-action solution is indicated for the treatment of bacterial ocular infections accompanied by inflammation and pain. Ofloxacin exerts its antibacterial effect by inhibiting bacterial DNA gyrase and topoisomerase IV, thereby preventing bacterial replication and effectively targeting a wide range of gram-positive and gram-negative pathogens commonly implicated in conjunctivitis, keratitis, and other external ocular infections.
Ketorolac provides potent anti-inflammatory and analgesic effects by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), leading to reduced prostaglandin synthesis, which alleviates ocular inflammation, redness, and discomfort. Ketoflox Ophthalmic Solution is particularly useful post-ocular surgery or in cases where infection and inflammation coexist, facilitating faster recovery and symptom relief.
The solution should be administered as directed by a healthcare professional, typically one to two drops into the affected eye(s) every 6 to 8 hours. Caution is advised in patients with hypersensitivity to either component, and prolonged use should be avoided to prevent potential adverse effects such as corneal toxicity or secondary infections. Proper hygiene and adherence to prescribed dosing are essential to ensure therapeutic efficacy and safety.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Information regarding the use of Ketoflox Ophthalmic Solution during pregnancy is not available. Please consult your doctor.
High Risk
Information regarding the use of Ketoflox Ophthalmic Solution during breastfeeding is not available. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
Ketoflox Ophthalmic Solution may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.
Consult Doctor
No interaction found/established
Regular Checkup
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