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  4. K-Pio-M Tablet ER
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K-Pio-M Tablet ER

Images are for reference. Actual packaging may vary.

1 units • OtherPrescription requiredSchedule H

K-Pio-M Tablet ER

Pioglitazone (15mg) + Metformin (500mg)

Blue Cross Laboratories LtdAnti-Diabetic
₹51.56

1 units • Other

A valid prescription is required for this medicine.

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Active composition

Metformin 500 mg

+1 more active ingredient

How It Works

Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.

Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-γ), enhancing insulin sensitivity and glucose metabolism.

Medicine Strength
500 mg

All Active Ingredients

Metformin500 mg
Pioglitazone15 mg

Uses & Benefits

Medical applications

Diabetes

K-Pio-M Tablet ER is a combination oral antidiabetic medication containing Pioglitazone 15 mg and Metformin 500 mg in an extended-release formulation. It is indicated for the management of type 2 diabetes mellitus, particularly in patients who are inadequately controlled on diet and exercise alone. Pioglitazone, a thiazolidinedione, improves insulin sensitivity in peripheral tissues by activating peroxisome proliferator-activated receptor gamma (PPAR-γ), thereby enhancing glucose uptake and utilization.

Read full descriptionShow less⌄

Metformin, a biguanide, primarily acts by decreasing hepatic glucose production and improving peripheral glucose uptake, contributing to better glycemic control. The extended-release formulation allows for once-daily dosing, improving patient compliance and minimizing gastrointestinal side effects commonly associated with immediate-release metformin. K-Pio-M Tablet ER is to be used as part of a comprehensive diabetes management plan, including diet, exercise, and regular monitoring of blood glucose levels.

It is contraindicated in patients with severe renal impairment, acute or chronic metabolic acidosis, and hypersensitivity to its components. Common adverse effects may include gastrointestinal disturbances, weight gain, edema, and a risk of hypoglycemia when used with other antidiabetic agents. Regular monitoring of liver function and hematologic parameters is recommended during therapy.

K-Pio-M Tablet ER packaging
Medicine details

K-Pio-M Tablet ER

Composition

2 ingredients
  • Metformin500 mg
  • Pioglitazone15 mg
Dosage & how to useRead the usage informationSafety & side effectsReview precautions

Dosage & How to Use

Dosage information not available. Please consult your doctor or pharmacist.

Safety Advice

Important precautions

Side effects

Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.

Safety Advice

Alcohol

K-Pio-M Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

High Risk

Pregnancy

K-Pio-M Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Medical Advice

Driving

K-Pio-M Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of K-Pio-M Tablet ER may be needed. Please consult your doctor. Use of K-Pio-M Tablet ER is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

Exercise Caution

Breastfeeding

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Consult Doctor

Kidney

K-Pio-M Tablet ER should be used with caution in patients with liver disease. Dose adjustment of K-Pio-M Tablet ER may be needed. Please consult your doctor. K-Pio-M Tablet ER is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

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Customer Reviews

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