
Metformin (500mg) + Teneligliptin (20mg)
Active composition
+1 more active ingredient
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Teneligliptin inhibits DPP-4, increasing incretin levels and enhancing insulin secretion.
Medical applications
Joten M Tablet PR is a combination oral antidiabetic medication containing Metformin 500 mg and Teneligliptin 20 mg, indicated for the management of type 2 diabetes mellitus. Metformin, a biguanide, primarily acts by decreasing hepatic glucose production, improving insulin sensitivity, and enhancing peripheral glucose uptake, thereby aiding in glycemic control. Teneligliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, enhances incretin hormone levels, which increase insulin secretion and decrease glucagon release in a glucose-dependent manner. The extended-release formulation of Joten M Tablet PR allows for sustained plasma concentration, improving patient compliance and reducing gastrointestinal side effects commonly associated with metformin. This combination therapy is particularly beneficial for patients inadequately controlled on metformin monotherapy or those requiring dual mechanisms to achieve optimal glycemic targets. Joten M Tablet PR should be used as an adjunct to diet and exercise to improve glycemic control. Caution is advised in patients with renal impairment, hepatic dysfunction, or a history of pancreatitis. Common adverse effects may include gastrointestinal disturbances, hypoglycemia (especially when combined with other antidiabetics), and rare cases of lactic acidosis. Regular monitoring of blood glucose, renal function, and overall metabolic status is recommended during therapy.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Joten M Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Joten M Tablet PR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Joten M Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Joten M Tablet PR may be needed. Please consult your doctor. Use of Joten M Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Exercise Caution
It is not known whether Joten M Tablet PR alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Consult Doctor
Joten M Tablet PR is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
0 reviews for Joten M Tablet PR

Metformin (500mg) + Teneligliptin (20mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Teneligliptin inhibits DPP-4, increasing incretin levels and enhancing insulin secretion.
Medical applications
Joten M Tablet PR is a combination oral antidiabetic medication containing Metformin 500 mg and Teneligliptin 20 mg, indicated for the management of type 2 diabetes mellitus. Metformin, a biguanide, primarily acts by decreasing hepatic glucose production, improving insulin sensitivity, and enhancing peripheral glucose uptake, thereby aiding in glycemic control. Teneligliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, enhances incretin hormone levels, which increase insulin secretion and decrease glucagon release in a glucose-dependent manner. The extended-release formulation of Joten M Tablet PR allows for sustained plasma concentration, improving patient compliance and reducing gastrointestinal side effects commonly associated with metformin. This combination therapy is particularly beneficial for patients inadequately controlled on metformin monotherapy or those requiring dual mechanisms to achieve optimal glycemic targets. Joten M Tablet PR should be used as an adjunct to diet and exercise to improve glycemic control. Caution is advised in patients with renal impairment, hepatic dysfunction, or a history of pancreatitis. Common adverse effects may include gastrointestinal disturbances, hypoglycemia (especially when combined with other antidiabetics), and rare cases of lactic acidosis. Regular monitoring of blood glucose, renal function, and overall metabolic status is recommended during therapy.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Joten M Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Joten M Tablet PR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Joten M Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Joten M Tablet PR may be needed. Please consult your doctor. Use of Joten M Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Exercise Caution
It is not known whether Joten M Tablet PR alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Consult Doctor
Joten M Tablet PR is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
0 reviews for Joten M Tablet PR













