
Diclofenac (100mg)
Active composition
Diclofenac inhibits COX-1 and COX-2 enzymes, leading to decreased synthesis of prostaglandins, which mediate pain and inflammation.
Medical applications
Jonac 100mg Suppository contains Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) indicated for the management of mild to moderate pain and inflammation associated with conditions such as musculoskeletal disorders, postoperative pain, and dysmenorrhea. Diclofenac exerts its therapeutic effect by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, thereby reducing the synthesis of prostaglandins, which are mediators of inflammation and pain. The suppository formulation allows for rapid absorption through the rectal mucosa, providing an alternative route of administration for patients who experience difficulty with oral intake or require localized drug delivery. Jonac 100mg Suppository is typically administered rectally, with dosage and duration tailored according to the severity of symptoms and patient response. It is contraindicated in patients with hypersensitivity to diclofenac, aspirin, or other NSAIDs, as well as those with active gastrointestinal bleeding, severe hepatic or renal impairment, and certain cardiovascular conditions. Caution is advised in patients with a history of gastrointestinal ulcers or bleeding, and concurrent use with other NSAIDs or anticoagulants should be avoided to minimize adverse effects. Common side effects may include gastrointestinal discomfort, nausea, and local irritation at the site of administration. Patients should consult healthcare professionals before use to ensure appropriate indication and dosing.
How to use Jonac Suppository Remove the wrapper from the suppository before inserting it. Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
No interaction found/established
High Risk
Jonac 100mg Suppository may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
Jonac 100mg Suppository should be used with caution in patients with liver disease. Dose adjustment of Jonac 100mg Suppository may be needed. Please consult your doctor.
Regular Checkup
Jonac 100mg Suppository is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
There is limited information available on the use of Jonac 100mg Suppository in patients with kidney disease. Please consult your doctor.
Regular Checkup
0 reviews for Jonac 100mg Suppository

Diclofenac (100mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
Diclofenac inhibits COX-1 and COX-2 enzymes, leading to decreased synthesis of prostaglandins, which mediate pain and inflammation.
Medical applications
Jonac 100mg Suppository contains Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) indicated for the management of mild to moderate pain and inflammation associated with conditions such as musculoskeletal disorders, postoperative pain, and dysmenorrhea. Diclofenac exerts its therapeutic effect by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, thereby reducing the synthesis of prostaglandins, which are mediators of inflammation and pain. The suppository formulation allows for rapid absorption through the rectal mucosa, providing an alternative route of administration for patients who experience difficulty with oral intake or require localized drug delivery. Jonac 100mg Suppository is typically administered rectally, with dosage and duration tailored according to the severity of symptoms and patient response. It is contraindicated in patients with hypersensitivity to diclofenac, aspirin, or other NSAIDs, as well as those with active gastrointestinal bleeding, severe hepatic or renal impairment, and certain cardiovascular conditions. Caution is advised in patients with a history of gastrointestinal ulcers or bleeding, and concurrent use with other NSAIDs or anticoagulants should be avoided to minimize adverse effects. Common side effects may include gastrointestinal discomfort, nausea, and local irritation at the site of administration. Patients should consult healthcare professionals before use to ensure appropriate indication and dosing.
How to use Jonac Suppository Remove the wrapper from the suppository before inserting it. Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
No interaction found/established
High Risk
Jonac 100mg Suppository may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
Jonac 100mg Suppository should be used with caution in patients with liver disease. Dose adjustment of Jonac 100mg Suppository may be needed. Please consult your doctor.
Regular Checkup
Jonac 100mg Suppository is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
There is limited information available on the use of Jonac 100mg Suppository in patients with kidney disease. Please consult your doctor.
Regular Checkup
0 reviews for Jonac 100mg Suppository











