Itrazviv Plus Cream
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Tube of 15 gm • GelPrescription requiredSchedule H
Itrazviv Plus Cream
Ofloxacin (0.75% w/w) + Ornidazole (2% w/w) + Itraconazole (1% w/w) + Clobetasol (0.05% w/w)
₹95.00
Tube of 15 gm • Gel
A valid prescription is required for this medicine.
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Active composition
Clobetasol
+3 more active ingredients
How It Works
Clobetasol binds to glucocorticoid receptors, inhibiting the transcription of pro-inflammatory genes and reducing inflammation.
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Itraconazole inhibits the synthesis of ergosterol, disrupting fungal cell membrane integrity.
Ornidazole disrupts DNA synthesis in protozoan organisms, leading to cell death and resolution of infection.
All Active Ingredients
Clobetasol
Ofloxacin
Itraconazole
Ornidazole
Uses & Benefits
Medical applications
Anti-inflammatoryInflammationInfectionBacterial
Itrazviv Plus Cream is a topical formulation combining Ofloxacin (0.75% w/w), Ornidazole (2% w/w), Itraconazole (1% w/w), and Clobetasol (0.05% w/w) designed for the effective management of mixed bacterial, protozoal, and fungal skin infections accompanied by inflammation and pruritus. Ofloxacin, a broad-spectrum fluoroquinolone antibiotic, targets susceptible Gram-positive and Gram-negative bacteria by inhibiting DNA gyrase, thereby preventing bacterial replication.
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Ornidazole, a nitroimidazole derivative, exhibits potent antiprotozoal and anaerobic antibacterial activity, disrupting DNA synthesis in protozoa and anaerobic bacteria. Itraconazole, a triazole antifungal agent, impedes fungal ergosterol synthesis by inhibiting cytochrome P450-dependent 14α-demethylase, leading to impaired fungal cell membrane integrity. Clobetasol propionate, a potent topical corticosteroid, provides anti-inflammatory, antipruritic, and vasoconstrictive effects, reducing erythema, edema, and discomfort associated with inflammatory dermatoses.
This combination is indicated for complex dermal infections where multiple pathogens coexist, particularly in cases resistant to monotherapy. The cream should be applied as directed, avoiding prolonged use to minimize corticosteroid-related adverse effects such as skin atrophy or hypothalamic-pituitary-adrenal axis suppression. Caution is advised in patients with hypersensitivity to any component, and use on extensive areas or broken skin should be under medical supervision.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Pregnancy
Information regarding the use of Itrazviv Plus Cream during pregnancy is not available. Please consult your doctor.
Medical Advice
Driving
No interaction found/established
Exercise Caution
Breastfeeding
No interaction found/established
Consult Doctor
Kidney
No interaction found/established
Regular Checkup
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