Isotrate 20 Tablet contains Isosorbide Mononitrate 20 mg, a nitrate class medication primarily indicated for the prevention and management of angina pectoris due to coronary artery disease. Isosorbide Mononitrate acts as a vasodilator by relaxing vascular smooth muscle, leading to the dilation of peripheral veins and arteries. This reduces myocardial oxygen demand by decreasing preload and afterload, thereby alleviating chest pain associated with ischemic heart conditions. The extended-release formulation of Isotrate 20 ensures a sustained therapeutic effect, allowing for once or twice daily dosing to maintain stable plasma concentrations. It is commonly prescribed for chronic angina prophylaxis rather than acute angina attacks. Patients should be advised to avoid sudden discontinuation to prevent rebound angina. Common side effects may include headache, dizziness, hypotension, and flushing, which are generally dose-related and tend to diminish with continued use. Isotrate 20 should be used cautiously in patients with hypotension, severe anemia, or increased intracranial pressure. Concurrent use with phosphodiesterase inhibitors is contraindicated due to the risk of severe hypotension. Regular monitoring and adherence to prescribed dosage are essential to optimize therapeutic outcomes and minimize adverse effects.

Dosage & How to Use