
Isosorbide Mononitrate (40mg)
Active composition
Isosorbide Mononitrate releases nitric oxide, leading to vasodilation and reduced myocardial oxygen demand.
Medical applications
Ismo Retard Tablet ER contains Isosorbide Mononitrate 40 mg, a long-acting nitrate used primarily for the prevention and management of angina pectoris due to coronary artery disease. Isosorbide Mononitrate acts as a vasodilator by releasing nitric oxide, which relaxes vascular smooth muscle, leading to the dilation of peripheral veins and arteries. This results in reduced myocardial oxygen demand by decreasing preload and afterload, thereby alleviating anginal symptoms. The extended-release formulation ensures a sustained therapeutic effect, maintaining stable plasma concentrations over an extended period and minimizing the frequency of dosing. Ismo Retard Tablet ER is indicated for prophylactic treatment rather than acute angina attacks. It should be administered orally, typically once daily, preferably in the morning to reduce the risk of tolerance development. Common side effects may include headache, dizziness, hypotension, and flushing. Caution is advised in patients with hypotension, severe anemia, or those concurrently using phosphodiesterase inhibitors due to the risk of severe hypotension. Regular monitoring and adherence to prescribed dosing schedules are essential to optimize therapeutic outcomes and minimize adverse effects. Ismo Retard Tablet ER should be used under medical supervision with consideration of individual patient risk factors.
How to use Ismo Tablet ER Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ismo Retard Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Consuming alcohol while taking Ismo Retard Tablet ER may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
High Risk
Ismo Retard Tablet ER may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Ismo Retard Tablet ER is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Ismo Retard Tablet ER may not be needed in these patients. Please consult your doctor.
Regular Checkup
Ismo Retard Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Ismo Retard Tablet ER is safe to use in patients with kidney disease. No dose adjustment of Ismo Retard Tablet ER is recommended. However, talk to your doctor if you have any underlying kidney disease.
Regular Checkup
0 reviews for Ismo Retard Tablet ER

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Active composition
Isosorbide Mononitrate releases nitric oxide, leading to vasodilation and reduced myocardial oxygen demand.
Medical applications
Ismo Retard Tablet ER contains Isosorbide Mononitrate 40 mg, a long-acting nitrate used primarily for the prevention and management of angina pectoris due to coronary artery disease. Isosorbide Mononitrate acts as a vasodilator by releasing nitric oxide, which relaxes vascular smooth muscle, leading to the dilation of peripheral veins and arteries. This results in reduced myocardial oxygen demand by decreasing preload and afterload, thereby alleviating anginal symptoms. The extended-release formulation ensures a sustained therapeutic effect, maintaining stable plasma concentrations over an extended period and minimizing the frequency of dosing. Ismo Retard Tablet ER is indicated for prophylactic treatment rather than acute angina attacks. It should be administered orally, typically once daily, preferably in the morning to reduce the risk of tolerance development. Common side effects may include headache, dizziness, hypotension, and flushing. Caution is advised in patients with hypotension, severe anemia, or those concurrently using phosphodiesterase inhibitors due to the risk of severe hypotension. Regular monitoring and adherence to prescribed dosing schedules are essential to optimize therapeutic outcomes and minimize adverse effects. Ismo Retard Tablet ER should be used under medical supervision with consideration of individual patient risk factors.
How to use Ismo Tablet ER Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ismo Retard Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Consuming alcohol while taking Ismo Retard Tablet ER may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
High Risk
Ismo Retard Tablet ER may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Ismo Retard Tablet ER is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Ismo Retard Tablet ER may not be needed in these patients. Please consult your doctor.
Regular Checkup
Ismo Retard Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Ismo Retard Tablet ER is safe to use in patients with kidney disease. No dose adjustment of Ismo Retard Tablet ER is recommended. However, talk to your doctor if you have any underlying kidney disease.
Regular Checkup
0 reviews for Ismo Retard Tablet ER















