Insuvil-DP 100/10 Tablet SR is a combination oral antidiabetic medication containing Dapagliflozin 10 mg and Vildagliptin 100 mg, designed for sustained release to improve glycemic control in patients with type 2 diabetes mellitus. Dapagliflozin, a selective sodium-glucose co-transporter 2 (SGLT2) inhibitor, reduces renal glucose reabsorption, promoting urinary glucose excretion and thereby lowering blood glucose levels. Vildagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, enhances the incretin system by preventing the degradation of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), resulting in increased insulin secretion and decreased glucagon release in a glucose-dependent manner. The combined mechanism addresses hyperglycemia through complementary pathways, improving fasting and postprandial glucose control. Insuvil-DP 100/10 SR is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes inadequately controlled by either agent alone or other antidiabetic therapies. The sustained-release formulation ensures steady plasma drug levels, enhancing compliance and minimizing peak-related adverse effects. Common side effects may include urinary tract infections, genital infections, hypoglycemia (especially when used with insulin or sulfonylureas), and gastrointestinal disturbances. Use with caution in patients with renal impairment, and contraindicated in type 1 diabetes or diabetic ketoacidosis. Regular monitoring of renal function and glycemic status is recommended during therapy.

Dosage & How to Use