Imutdol-P Tablet
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Tramadol (37.5mg) + Paracetamol (325mg)
1 units • Other
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Active composition
+1 more active ingredient
Tramadol binds to mu-opioid receptors and inhibits the reuptake of norepinephrine and serotonin, modulating pain perception.
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Medical applications
Imutdol-P Tablet is a combination analgesic formulation containing Tramadol hydrochloride 37.5 mg and Paracetamol 325 mg, designed for the management of moderate to moderately severe pain. Tramadol, a centrally acting synthetic opioid analgesic, exerts its effect by binding to the mu-opioid receptor and inhibiting the reuptake of norepinephrine and serotonin, thereby modulating pain perception.
Paracetamol, a widely used non-opioid analgesic and antipyretic agent, acts primarily through central inhibition of prostaglandin synthesis, contributing to its analgesic and antipyretic properties. The synergistic combination in Imutdol-P provides enhanced analgesia while potentially reducing the required dose of tramadol, thereby minimizing opioid-related adverse effects. This tablet is indicated for conditions such as postoperative pain, musculoskeletal pain, osteoarthritis, and other painful conditions where moderate analgesia is required.
Imutdol-P should be administered as per physician’s guidance, with careful consideration of contraindications including hypersensitivity to either component, severe respiratory depression, and acute intoxication with alcohol or central nervous system depressants. Caution is advised in patients with hepatic or renal impairment, history of seizures, or those on concomitant serotonergic drugs due to the risk of serotonin syndrome.
Adverse effects may include nausea, dizziness, constipation, and somnolence. Proper patient counseling and adherence to prescribed dosage are essential to optimize therapeutic outcomes and minimize risks.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Imutdol-P Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Imutdol-P Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.
Medical Advice
Imutdol-P Tablet should be used with caution in patients with kidney disease. Dose adjustment of Imutdol-P Tablet may be needed. Please consult your doctor.
Exercise Caution
Imutdol-P Tablet may cause side effects which could affect your ability to drive.
Consult Doctor
Imutdol-P Tablet should be used with caution in patients with liver disease. Dose adjustment of Imutdol-P Tablet may be needed. Please consult your doctor. However, the use of Imutdol-P Tablet is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
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