Ignalis 100 Tablet
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Sitagliptin (100mg)
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
Sitagliptin inhibits DPP-4, increasing incretin levels, which stimulate insulin release and reduce glucagon secretion.
Medical applications
Ignalis 100 Tablet contains Sitagliptin 100 mg, a potent dipeptidyl peptidase-4 (DPP-4) inhibitor indicated for the management of type 2 diabetes mellitus. Sitagliptin enhances the body's ability to regulate blood glucose by increasing the levels of incretin hormones, which stimulate insulin release from pancreatic beta cells and suppress glucagon secretion from alpha cells in a glucose-dependent manner.
This dual action helps improve glycemic control without causing significant hypoglycemia. Ignalis 100 is typically prescribed as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes, either as monotherapy or in combination with other antidiabetic agents such as metformin, sulfonylureas, or insulin. The medication is administered orally once daily, with or without food.
Clinical studies have demonstrated that Sitagliptin effectively lowers HbA1c levels and fasting plasma glucose, contributing to improved long-term glycemic management. Common adverse effects may include nasopharyngitis, headache, and upper respiratory tract infections, while serious side effects are rare but may include pancreatitis and hypersensitivity reactions. Regular monitoring of renal function is recommended, as dose adjustments may be necessary in patients with renal impairment.
Ignalis 100 should be used under medical supervision to optimize diabetes management and minimize complications.
Pyrazine-derivative
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Information regarding the use of Ignalis 100 Tablet during pregnancy is not available. Please consult your doctor.
High Risk
Ignalis 100 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Ignalis 100 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Ignalis 100 Tablet may be needed. Please consult your doctor.
Exercise Caution
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Consult Doctor
Ignalis 100 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Ignalis 100 Tablet may not be needed in these patients. Please consult your doctor. However, Ignalis 100 Tablet has not been studied in patients with severe hepatic impairment and is not recommended for use in such patients.
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