
Ceftriaxone (1000mg) + Sulbactam (500mg)
Active composition
+1 more active ingredient
Ceftriaxone binds to penicillin-binding proteins, inhibiting cell wall synthesis and leading to bacterial lysis.
Sulbactam irreversibly binds to beta-lactamase enzymes, preventing them from inactivating beta-lactam antibiotics.
Medical applications
Icocef 1000mg/500mg Injection is a combination antibiotic formulation containing Ceftriaxone 1000mg and Sulbactam 500mg, indicated for the treatment of a wide range of bacterial infections. Ceftriaxone, a third-generation cephalosporin, exhibits broad-spectrum bactericidal activity by inhibiting bacterial cell wall synthesis, while Sulbactam, a beta-lactamase inhibitor, enhances the efficacy of Ceftriaxone by preventing enzymatic degradation of the antibiotic. This synergistic combination is effective against both gram-positive and gram-negative pathogens, including beta-lactamase producing strains. Icocef Injection is commonly employed in the management of respiratory tract infections, urinary tract infections, intra-abdominal infections, skin and soft tissue infections, bone and joint infections, and septicemia. The formulation is administered via intravenous or intramuscular injection, ensuring rapid systemic distribution and achieving therapeutic concentrations in various tissues and body fluids. Dosage and duration of therapy should be individualized based on the severity and type of infection, patient’s renal and hepatic function, and clinical response. Adverse effects are generally mild and may include local injection site reactions, gastrointestinal disturbances, and hypersensitivity reactions. Caution is advised in patients with known allergy to cephalosporins or penicillins. Icocef 1000mg/500mg Injection should be used under strict medical supervision to optimize therapeutic outcomes and minimize resistance development.
How to use Icocef Injection Your doctor or nurse will give you this medicine. Kindly do not self administer.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Consuming alcohol with Icocef 1000mg/500mg Injection does not cause any harmful side effects.
High Risk
Icocef 1000mg/500mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Medical Advice
Icocef 1000mg/500mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Icocef 1000mg/500mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Icocef 1000mg/500mg Injection may be needed. Please consult your doctor. Dose adjustment of Icocef 1000mg/500mg Injection is not recommended in patients with mild to moderate liver disease.
Regular Checkup
Icocef 1000mg/500mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Consult Doctor
There is limited information available on the use of Icocef 1000mg/500mg Injection in patients with kidney disease. Please consult your doctor.
Regular Checkup
0 reviews for Icocef 1000mg/500mg Injection

Ceftriaxone (1000mg) + Sulbactam (500mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Ceftriaxone binds to penicillin-binding proteins, inhibiting cell wall synthesis and leading to bacterial lysis.
Sulbactam irreversibly binds to beta-lactamase enzymes, preventing them from inactivating beta-lactam antibiotics.
Medical applications
Icocef 1000mg/500mg Injection is a combination antibiotic formulation containing Ceftriaxone 1000mg and Sulbactam 500mg, indicated for the treatment of a wide range of bacterial infections. Ceftriaxone, a third-generation cephalosporin, exhibits broad-spectrum bactericidal activity by inhibiting bacterial cell wall synthesis, while Sulbactam, a beta-lactamase inhibitor, enhances the efficacy of Ceftriaxone by preventing enzymatic degradation of the antibiotic. This synergistic combination is effective against both gram-positive and gram-negative pathogens, including beta-lactamase producing strains. Icocef Injection is commonly employed in the management of respiratory tract infections, urinary tract infections, intra-abdominal infections, skin and soft tissue infections, bone and joint infections, and septicemia. The formulation is administered via intravenous or intramuscular injection, ensuring rapid systemic distribution and achieving therapeutic concentrations in various tissues and body fluids. Dosage and duration of therapy should be individualized based on the severity and type of infection, patient’s renal and hepatic function, and clinical response. Adverse effects are generally mild and may include local injection site reactions, gastrointestinal disturbances, and hypersensitivity reactions. Caution is advised in patients with known allergy to cephalosporins or penicillins. Icocef 1000mg/500mg Injection should be used under strict medical supervision to optimize therapeutic outcomes and minimize resistance development.
How to use Icocef Injection Your doctor or nurse will give you this medicine. Kindly do not self administer.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Consuming alcohol with Icocef 1000mg/500mg Injection does not cause any harmful side effects.
High Risk
Icocef 1000mg/500mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Medical Advice
Icocef 1000mg/500mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Icocef 1000mg/500mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Icocef 1000mg/500mg Injection may be needed. Please consult your doctor. Dose adjustment of Icocef 1000mg/500mg Injection is not recommended in patients with mild to moderate liver disease.
Regular Checkup
Icocef 1000mg/500mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Consult Doctor
There is limited information available on the use of Icocef 1000mg/500mg Injection in patients with kidney disease. Please consult your doctor.
Regular Checkup
0 reviews for Icocef 1000mg/500mg Injection















