
Ibuprofen (400mg) + Paracetamol (325mg)
Active composition
+1 more active ingredient
Ibuprofen inhibits cyclooxygenase (COX) enzymes, reducing the production of prostaglandins involved in inflammation and pain.
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Medical applications
Ibugesic Plus Tablet is a combination analgesic and antipyretic formulation containing Ibuprofen 400 mg and Paracetamol 325 mg, designed for the effective management of mild to moderate pain and fever. Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), exerts its therapeutic effects by inhibiting cyclooxygenase (COX) enzymes, thereby reducing the synthesis of prostaglandins responsible for inflammation, pain, and fever. Paracetamol (acetaminophen) acts centrally to inhibit prostaglandin synthesis, providing analgesic and antipyretic benefits without significant anti-inflammatory activity. The synergistic action of these two agents offers enhanced pain relief compared to monotherapy, making Ibugesic Plus suitable for conditions such as musculoskeletal pain, dental pain, headache, postoperative pain, and febrile episodes. It is generally well tolerated when used as directed; however, caution is advised in patients with a history of gastrointestinal ulcers, renal or hepatic impairment, and hypersensitivity to NSAIDs or paracetamol. The medication should be administered with food to minimize gastrointestinal discomfort. Dosage adjustments may be necessary in special populations, and prolonged use should be avoided unless supervised by a healthcare professional. Ibugesic Plus Tablet provides a balanced approach to pain and fever management, combining rapid onset and sustained relief.
How to use Ibugesic Plus Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ibugesic Plus Tablet is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Ibugesic Plus Tablet.
High Risk
Ibugesic Plus Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Ibugesic Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Ibugesic Plus Tablet may be needed. Please consult your doctor. However, the use of Ibugesic Plus Tablet is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
Ibugesic Plus Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Ibugesic Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment of Ibugesic Plus Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Ibugesic Plus Tablet

Ibuprofen (400mg) + Paracetamol (325mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Ibuprofen inhibits cyclooxygenase (COX) enzymes, reducing the production of prostaglandins involved in inflammation and pain.
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Medical applications
Ibugesic Plus Tablet is a combination analgesic and antipyretic formulation containing Ibuprofen 400 mg and Paracetamol 325 mg, designed for the effective management of mild to moderate pain and fever. Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), exerts its therapeutic effects by inhibiting cyclooxygenase (COX) enzymes, thereby reducing the synthesis of prostaglandins responsible for inflammation, pain, and fever. Paracetamol (acetaminophen) acts centrally to inhibit prostaglandin synthesis, providing analgesic and antipyretic benefits without significant anti-inflammatory activity. The synergistic action of these two agents offers enhanced pain relief compared to monotherapy, making Ibugesic Plus suitable for conditions such as musculoskeletal pain, dental pain, headache, postoperative pain, and febrile episodes. It is generally well tolerated when used as directed; however, caution is advised in patients with a history of gastrointestinal ulcers, renal or hepatic impairment, and hypersensitivity to NSAIDs or paracetamol. The medication should be administered with food to minimize gastrointestinal discomfort. Dosage adjustments may be necessary in special populations, and prolonged use should be avoided unless supervised by a healthcare professional. Ibugesic Plus Tablet provides a balanced approach to pain and fever management, combining rapid onset and sustained relief.
How to use Ibugesic Plus Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ibugesic Plus Tablet is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Ibugesic Plus Tablet.
High Risk
Ibugesic Plus Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Ibugesic Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Ibugesic Plus Tablet may be needed. Please consult your doctor. However, the use of Ibugesic Plus Tablet is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
Ibugesic Plus Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Ibugesic Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment of Ibugesic Plus Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Ibugesic Plus Tablet











