
Ornidazole (500mg) + Ofloxacin (200mg)
Active composition
+1 more active ingredient
Ornidazole disrupts DNA synthesis in protozoan organisms, leading to cell death and resolution of infection.
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Medical applications
Horn O 200mg/500mg Tablet is a combination antibiotic formulation containing Ofloxacin 200mg and Ornidazole 500mg, indicated for the treatment of mixed bacterial and protozoal infections. Ofloxacin, a fluoroquinolone antibiotic, exerts its effect by inhibiting bacterial DNA gyrase and topoisomerase IV, thereby preventing bacterial replication and transcription. Ornidazole, a nitroimidazole derivative, is effective against anaerobic bacteria and protozoa by disrupting DNA synthesis and causing cell death. This synergistic combination is particularly useful in managing infections where both aerobic and anaerobic pathogens are implicated, such as gastrointestinal infections, genitourinary tract infections, respiratory tract infections, skin and soft tissue infections, and certain sexually transmitted infections. Horn O should be administered as prescribed by a healthcare professional, with dosage adjusted according to the severity of infection and patient-specific factors including renal function. Caution is advised in patients with a history of hypersensitivity to fluoroquinolones or nitroimidazoles. Common adverse effects may include gastrointestinal disturbances, headache, dizziness, and, rarely, tendonitis or neuropathy. It is contraindicated during pregnancy and lactation unless clearly necessary. Proper adherence to the prescribed regimen is essential to prevent resistance development and ensure therapeutic efficacy.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Horn O 200mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Information regarding the use of Horn O 200mg/500mg Tablet during breastfeeding is not available. Please consult your doctor.
Medical Advice
Horn O 200mg/500mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Horn O 200mg/500mg Tablet may be needed. Please consult your doctor.
Exercise Caution
Horn O 200mg/500mg Tablet may cause side effects which could affect your ability to drive.
Consult Doctor
Horn O 200mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Horn O 200mg/500mg Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Horn O 200mg/500mg Tablet

Ofloxacin (200mg) + Ornidazole (500mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Ornidazole disrupts DNA synthesis in protozoan organisms, leading to cell death and resolution of infection.
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Medical applications
Horn O 200mg/500mg Tablet is a combination antibiotic formulation containing Ofloxacin 200mg and Ornidazole 500mg, indicated for the treatment of mixed bacterial and protozoal infections. Ofloxacin, a fluoroquinolone antibiotic, exerts its effect by inhibiting bacterial DNA gyrase and topoisomerase IV, thereby preventing bacterial replication and transcription. Ornidazole, a nitroimidazole derivative, is effective against anaerobic bacteria and protozoa by disrupting DNA synthesis and causing cell death. This synergistic combination is particularly useful in managing infections where both aerobic and anaerobic pathogens are implicated, such as gastrointestinal infections, genitourinary tract infections, respiratory tract infections, skin and soft tissue infections, and certain sexually transmitted infections. Horn O should be administered as prescribed by a healthcare professional, with dosage adjusted according to the severity of infection and patient-specific factors including renal function. Caution is advised in patients with a history of hypersensitivity to fluoroquinolones or nitroimidazoles. Common adverse effects may include gastrointestinal disturbances, headache, dizziness, and, rarely, tendonitis or neuropathy. It is contraindicated during pregnancy and lactation unless clearly necessary. Proper adherence to the prescribed regimen is essential to prevent resistance development and ensure therapeutic efficacy.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Horn O 200mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Information regarding the use of Horn O 200mg/500mg Tablet during breastfeeding is not available. Please consult your doctor.
Medical Advice
Horn O 200mg/500mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Horn O 200mg/500mg Tablet may be needed. Please consult your doctor.
Exercise Caution
Horn O 200mg/500mg Tablet may cause side effects which could affect your ability to drive.
Consult Doctor
Horn O 200mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Horn O 200mg/500mg Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Horn O 200mg/500mg Tablet















