Hopace-MT 50 Tablet ER
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Metoprolol Succinate (50mg) + Ramipril (5mg)
1 units • Other
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Metoprolol Succinate blocks beta-1 adrenergic receptors, leading to decreased heart rate and contractility, thereby lowering blood pressure.
Ramipril inhibits the ACE enzyme, preventing the conversion of angiotensin I to angiotensin II, leading to vasodilation and reduced blood pressure.
Medical applications
Hopace-MT 50 Tablet ER is a combination antihypertensive medication containing Metoprolol Succinate 50 mg and Ramipril 5 mg, designed for extended-release administration. Metoprolol Succinate, a selective beta-1 adrenergic receptor blocker, reduces heart rate, myocardial contractility, and cardiac output, thereby lowering blood pressure and decreasing myocardial oxygen demand.
Ramipril, an angiotensin-converting enzyme (ACE) inhibitor, promotes vasodilation by inhibiting the conversion of angiotensin I to angiotensin II, reducing peripheral vascular resistance and aldosterone secretion. This synergistic combination effectively manages hypertension and reduces the risk of cardiovascular events such as myocardial infarction and stroke. Hopace-MT 50 Tablet ER is indicated for patients requiring multi-mechanistic blood pressure control, particularly those with concomitant cardiac conditions like ischemic heart disease or heart failure.
The extended-release formulation ensures a consistent plasma concentration, enhancing therapeutic efficacy and improving patient compliance by allowing once-daily dosing. Caution is advised in patients with bradycardia, hypotension, renal impairment, or a history of angioedema. Common adverse effects may include dizziness, fatigue, cough, and gastrointestinal disturbances. Regular monitoring of blood pressure, renal function, and electrolytes is recommended during therapy.
Hopace-MT 50 Tablet ER should be used under medical supervision to optimize cardiovascular outcomes safely.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Hopace-MT 50 Tablet ER is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Hopace-MT 50 Tablet ER is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Medical Advice
Hopace-MT 50 Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Hopace-MT 50 Tablet ER may be needed. Please consult your doctor. Regular monitoring of blood pressure is recommended for dose adjustment.
Exercise Caution
Hopace-MT 50 Tablet ER may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Hopace-MT 50 Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Hopace-MT 50 Tablet ER may be needed. Please consult your doctor. Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.
Regular Checkup
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