
Sitagliptin (50mg) + Metformin (500mg)
Active composition
+1 more active ingredient
Sitagliptin inhibits DPP-4, increasing incretin levels, which stimulate insulin release and reduce glucagon secretion.
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Medical applications
Hixita-M 50 Tablet is a combination oral antidiabetic medication containing Sitagliptin 50 mg and Metformin 500 mg, indicated for the management of type 2 diabetes mellitus. Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, enhances the levels of incretin hormones, thereby increasing insulin release and decreasing glucagon levels in a glucose-dependent manner. Metformin, a biguanide, primarily acts by reducing hepatic glucose production and improving insulin sensitivity in peripheral tissues. The synergistic action of these agents helps achieve better glycemic control by targeting multiple pathophysiological defects associated with type 2 diabetes. Hixita-M 50 is prescribed as an adjunct to diet and exercise to improve glycemic parameters in patients inadequately controlled on either component alone or when dual therapy is appropriate. It is contraindicated in patients with renal impairment, metabolic acidosis, or hypersensitivity to its components. Common adverse effects may include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal discomfort, which often subside with continued use. Regular monitoring of renal function and blood glucose levels is recommended during therapy. Dose adjustments may be necessary based on clinical response and tolerability. Hixita-M 50 should be used under medical supervision to optimize therapeutic outcomes and minimize potential risks.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Information regarding the use of Hixita-M 50 Tablet during pregnancy is not available. Please consult your doctor.
High Risk
Hixita-M 50 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Hixita-M 50 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Hixita-M 50 Tablet may be needed. Please consult your doctor. Use of Hixita-M 50 Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Exercise Caution
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Consult Doctor
Hixita-M 50 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
0 reviews for Hixita-M 50 Tablet

Sitagliptin (50mg) + Metformin (500mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Sitagliptin inhibits DPP-4, increasing incretin levels, which stimulate insulin release and reduce glucagon secretion.
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Medical applications
Hixita-M 50 Tablet is a combination oral antidiabetic medication containing Sitagliptin 50 mg and Metformin 500 mg, indicated for the management of type 2 diabetes mellitus. Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, enhances the levels of incretin hormones, thereby increasing insulin release and decreasing glucagon levels in a glucose-dependent manner. Metformin, a biguanide, primarily acts by reducing hepatic glucose production and improving insulin sensitivity in peripheral tissues. The synergistic action of these agents helps achieve better glycemic control by targeting multiple pathophysiological defects associated with type 2 diabetes. Hixita-M 50 is prescribed as an adjunct to diet and exercise to improve glycemic parameters in patients inadequately controlled on either component alone or when dual therapy is appropriate. It is contraindicated in patients with renal impairment, metabolic acidosis, or hypersensitivity to its components. Common adverse effects may include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal discomfort, which often subside with continued use. Regular monitoring of renal function and blood glucose levels is recommended during therapy. Dose adjustments may be necessary based on clinical response and tolerability. Hixita-M 50 should be used under medical supervision to optimize therapeutic outcomes and minimize potential risks.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Information regarding the use of Hixita-M 50 Tablet during pregnancy is not available. Please consult your doctor.
High Risk
Hixita-M 50 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Hixita-M 50 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Hixita-M 50 Tablet may be needed. Please consult your doctor. Use of Hixita-M 50 Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Exercise Caution
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Consult Doctor
Hixita-M 50 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
0 reviews for Hixita-M 50 Tablet













