
Paracetamol (325mg) + Polmacoxib (2mg)
Active composition
+1 more active ingredient
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Polmacoxib selectively inhibits COX-2, reducing the synthesis of inflammatory prostaglandins and alleviating pain.
Medical applications
Hisaka-P Tablet is a combination analgesic formulation containing Polmacoxib 2 mg and Paracetamol 325 mg, designed for the effective management of mild to moderate pain and inflammation. Polmacoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, provides anti-inflammatory and analgesic effects by reducing the synthesis of prostaglandins involved in the inflammatory process, thereby minimizing gastrointestinal side effects commonly associated with non-selective NSAIDs. Paracetamol, a widely used analgesic and antipyretic agent, complements Polmacoxib by inhibiting central prostaglandin synthesis, contributing to pain relief and fever reduction without significant anti-inflammatory action. The combination offers a synergistic effect, enhancing analgesic efficacy while potentially reducing the required dosage of each component, thus improving tolerability. Hisaka-P Tablet is indicated for conditions such as osteoarthritis, rheumatoid arthritis, musculoskeletal pain, dental pain, and postoperative pain management. It should be used with caution in patients with hepatic or renal impairment, and contraindicated in individuals with hypersensitivity to either component or a history of gastrointestinal bleeding. Regular monitoring and adherence to prescribed dosages are essential to minimize adverse effects. Hisaka-P Tablet provides a balanced therapeutic approach for pain and inflammation, optimizing patient comfort and functional recovery.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Information regarding the use of Hisaka-P Tablet during pregnancy is not available. Please consult your doctor.
High Risk
Information regarding the use of Hisaka-P Tablet during breastfeeding is not available. Please consult your doctor.
Medical Advice
There is limited information available on the use of Hisaka-P Tablet in patients with kidney disease. Please consult your doctor.
Exercise Caution
It is not known whether Hisaka-P Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Consult Doctor
There is limited information available on the use of Hisaka-P Tablet in patients with liver disease. Please consult your doctor.
Regular Checkup
0 reviews for Hisaka-P Tablet

Polmacoxib (2mg) + Paracetamol (325mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Polmacoxib selectively inhibits COX-2, reducing the synthesis of inflammatory prostaglandins and alleviating pain.
Medical applications
Hisaka-P Tablet is a combination analgesic formulation containing Polmacoxib 2 mg and Paracetamol 325 mg, designed for the effective management of mild to moderate pain and inflammation. Polmacoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, provides anti-inflammatory and analgesic effects by reducing the synthesis of prostaglandins involved in the inflammatory process, thereby minimizing gastrointestinal side effects commonly associated with non-selective NSAIDs. Paracetamol, a widely used analgesic and antipyretic agent, complements Polmacoxib by inhibiting central prostaglandin synthesis, contributing to pain relief and fever reduction without significant anti-inflammatory action. The combination offers a synergistic effect, enhancing analgesic efficacy while potentially reducing the required dosage of each component, thus improving tolerability. Hisaka-P Tablet is indicated for conditions such as osteoarthritis, rheumatoid arthritis, musculoskeletal pain, dental pain, and postoperative pain management. It should be used with caution in patients with hepatic or renal impairment, and contraindicated in individuals with hypersensitivity to either component or a history of gastrointestinal bleeding. Regular monitoring and adherence to prescribed dosages are essential to minimize adverse effects. Hisaka-P Tablet provides a balanced therapeutic approach for pain and inflammation, optimizing patient comfort and functional recovery.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Information regarding the use of Hisaka-P Tablet during pregnancy is not available. Please consult your doctor.
High Risk
Information regarding the use of Hisaka-P Tablet during breastfeeding is not available. Please consult your doctor.
Medical Advice
There is limited information available on the use of Hisaka-P Tablet in patients with kidney disease. Please consult your doctor.
Exercise Caution
It is not known whether Hisaka-P Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Consult Doctor
There is limited information available on the use of Hisaka-P Tablet in patients with liver disease. Please consult your doctor.
Regular Checkup
0 reviews for Hisaka-P Tablet











