
Ofloxacin (200mg) + Cefixime (200mg)
Active composition
+1 more active ingredient
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Cefixime disrupts the synthesis of the bacterial cell wall, leading to bacterial lysis and death.
Medical applications
Hifen Plus 200 mg/200 mg Tablet is a combination antibiotic formulation containing Cefixime 200 mg and Ofloxacin 200 mg, indicated for the treatment of a wide range of bacterial infections. Cefixime, a third-generation cephalosporin, exerts its bactericidal effect by inhibiting bacterial cell wall synthesis, while Ofloxacin, a fluoroquinolone antibiotic, inhibits bacterial DNA gyrase and topoisomerase IV, leading to disruption of DNA replication and transcription. This synergistic combination enhances antibacterial efficacy against both Gram-positive and Gram-negative pathogens, making it suitable for managing respiratory tract infections, urinary tract infections, gastrointestinal infections, and skin and soft tissue infections. Hifen Plus is particularly useful in cases where mixed infections or resistant bacterial strains are suspected. The tablet should be administered orally as prescribed by a healthcare professional, typically with or without food, ensuring adherence to the complete course to prevent resistance development. Caution is advised in patients with known hypersensitivity to cephalosporins or fluoroquinolones, and it is contraindicated in individuals with a history of tendon disorders related to fluoroquinolone use. Potential side effects include gastrointestinal disturbances, hypersensitivity reactions, and CNS effects such as dizziness. Consultation with a healthcare provider is essential before initiating therapy to ensure appropriate use and monitoring.
How to use Hifen Plus Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hifen Plus 200 mg/200 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Hifen Plus 200 mg/200 mg Tablet.
High Risk
Hifen Plus 200 mg/200 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Hifen Plus 200 mg/200 mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Hifen Plus 200 mg/200 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Hifen Plus 200 mg/200 mg Tablet may be needed. Please consult your doctor.
Regular Checkup
Hifen Plus 200 mg/200 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Hifen Plus 200 mg/200 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Hifen Plus 200 mg/200 mg Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Hifen Plus 200 mg/200 mg Tablet

Cefixime (200mg) + Ofloxacin (200mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Cefixime disrupts the synthesis of the bacterial cell wall, leading to bacterial lysis and death.
Medical applications
Hifen Plus 200 mg/200 mg Tablet is a combination antibiotic formulation containing Cefixime 200 mg and Ofloxacin 200 mg, indicated for the treatment of a wide range of bacterial infections. Cefixime, a third-generation cephalosporin, exerts its bactericidal effect by inhibiting bacterial cell wall synthesis, while Ofloxacin, a fluoroquinolone antibiotic, inhibits bacterial DNA gyrase and topoisomerase IV, leading to disruption of DNA replication and transcription. This synergistic combination enhances antibacterial efficacy against both Gram-positive and Gram-negative pathogens, making it suitable for managing respiratory tract infections, urinary tract infections, gastrointestinal infections, and skin and soft tissue infections. Hifen Plus is particularly useful in cases where mixed infections or resistant bacterial strains are suspected. The tablet should be administered orally as prescribed by a healthcare professional, typically with or without food, ensuring adherence to the complete course to prevent resistance development. Caution is advised in patients with known hypersensitivity to cephalosporins or fluoroquinolones, and it is contraindicated in individuals with a history of tendon disorders related to fluoroquinolone use. Potential side effects include gastrointestinal disturbances, hypersensitivity reactions, and CNS effects such as dizziness. Consultation with a healthcare provider is essential before initiating therapy to ensure appropriate use and monitoring.
How to use Hifen Plus Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hifen Plus 200 mg/200 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Hifen Plus 200 mg/200 mg Tablet.
High Risk
Hifen Plus 200 mg/200 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Hifen Plus 200 mg/200 mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Hifen Plus 200 mg/200 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Hifen Plus 200 mg/200 mg Tablet may be needed. Please consult your doctor.
Regular Checkup
Hifen Plus 200 mg/200 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Hifen Plus 200 mg/200 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Hifen Plus 200 mg/200 mg Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Hifen Plus 200 mg/200 mg Tablet















