Hftril 200 Tablet
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Strip of 7 tablets • TabletPrescription requiredSchedule H
Hftril 200 Tablet
Sacubitril (97mg) + Valsartan (103mg)
₹577.50
Strip of 7 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
Sacubitril 97 mg
+1 more active ingredient
How It Works
Sacubitril inhibits neprilysin, increasing levels of natriuretic peptides and promoting vasodilation.
Valsartan blocks the action of angiotensin II at its receptor sites, leading to vasodilation and decreased blood pressure.
Medicine Strength
97 mg
All Active Ingredients
Sacubitril97 mg
Valsartan103 mg
Uses & Benefits
Medical applications
Blood PressureHeart
Hftril 200 Tablet is a fixed-dose combination medication containing Sacubitril 97 mg and Valsartan 103 mg, indicated for the treatment of heart failure with reduced ejection fraction (HFrEF). Sacubitril, a neprilysin inhibitor, enhances the levels of natriuretic peptides by preventing their degradation, leading to vasodilation, natriuresis, and diuresis, which collectively reduce cardiac workload and improve cardiac function.
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Valsartan, an angiotensin II receptor blocker (ARB), inhibits the vasoconstrictive and aldosterone-secreting effects of angiotensin II, thereby lowering blood pressure and decreasing afterload. The synergistic action of these agents results in improved hemodynamics and reduced progression of heart failure. Hftril 200 is typically prescribed to patients who remain symptomatic despite optimal therapy with ACE inhibitors or ARBs alone.
Clinical trials have demonstrated that this combination significantly reduces cardiovascular mortality and hospitalization rates in heart failure patients. It is essential to monitor renal function, serum potassium, and blood pressure during therapy to mitigate potential adverse effects such as hypotension, hyperkalemia, and renal impairment. Hftril 200 should be used under strict medical supervision, with dosage adjustments based on individual patient response and tolerability.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Hftril 200 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Pregnancy
Hftril 200 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Driving
Hftril 200 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Hftril 200 Tablet may be needed. Please consult your doctor. Regular blood pressure monitoring is recommended. No dose adjustment is needed in patients with mild to moderate kidney disease.
Exercise Caution
Breastfeeding
It is not known whether Hftril 200 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Consult Doctor
Kidney
Hftril 200 Tablet should be used with caution in patients with liver disease. Dose adjustment of Hftril 200 Tablet may be needed. Please consult your doctor. However, no dose adjustment is recommended in patients with mild liver disease. Sacubitril+Valsartan is contraindicated in patients with severe liver disease.
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