
Ceftriaxone (250mg) + Sulbactam (125mg)
Active composition
+1 more active ingredient
Ceftriaxone binds to penicillin-binding proteins, inhibiting cell wall synthesis and leading to bacterial lysis.
Sulbactam irreversibly binds to beta-lactamase enzymes, preventing them from inactivating beta-lactam antibiotics.
Medical applications
Hexzone-SB 375mg Injection is a sterile, injectable formulation combining Ceftriaxone 250mg and Sulbactam 125mg, designed for the treatment of a broad spectrum of bacterial infections. Ceftriaxone, a third-generation cephalosporin antibiotic, exerts bactericidal activity by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Sulbactam, a beta-lactamase inhibitor, enhances the efficacy of Ceftriaxone by preventing the enzymatic degradation of the antibiotic by beta-lactamase-producing bacteria, thereby extending its spectrum of activity against resistant strains. Hexzone-SB is indicated for the management of infections caused by susceptible organisms, including lower respiratory tract infections, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, and septicemia. The injection is administered intravenously or intramuscularly, with dosage and duration tailored according to the severity of infection and patient response. It is contraindicated in patients with known hypersensitivity to cephalosporins, penicillins, or beta-lactamase inhibitors. Caution is advised in patients with renal or hepatic impairment. Adverse reactions may include hypersensitivity reactions, gastrointestinal disturbances, and local injection site reactions. Hexzone-SB 375mg Injection should be used under strict medical supervision, adhering to recommended guidelines to minimize resistance development and ensure therapeutic efficacy.
How to use Hexzone-SB Injection Your doctor or nurse will give you this medicine. Kindly do not self administer.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Consuming alcohol with Hexzone-SB 375mg Injection does not cause any harmful side effects.
High Risk
Hexzone-SB 375mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Medical Advice
Hexzone-SB 375mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Hexzone-SB 375mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Hexzone-SB 375mg Injection may be needed. Please consult your doctor. Dose adjustment of Hexzone-SB 375mg Injection is not recommended in patients with mild to moderate liver disease.
Regular Checkup
Hexzone-SB 375mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Consult Doctor
There is limited information available on the use of Hexzone-SB 375mg Injection in patients with kidney disease. Please consult your doctor.
Regular Checkup
0 reviews for Hexzone-SB 375mg Injection

Ceftriaxone (250mg) + Sulbactam (125mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Ceftriaxone binds to penicillin-binding proteins, inhibiting cell wall synthesis and leading to bacterial lysis.
Sulbactam irreversibly binds to beta-lactamase enzymes, preventing them from inactivating beta-lactam antibiotics.
Medical applications
Hexzone-SB 375mg Injection is a sterile, injectable formulation combining Ceftriaxone 250mg and Sulbactam 125mg, designed for the treatment of a broad spectrum of bacterial infections. Ceftriaxone, a third-generation cephalosporin antibiotic, exerts bactericidal activity by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Sulbactam, a beta-lactamase inhibitor, enhances the efficacy of Ceftriaxone by preventing the enzymatic degradation of the antibiotic by beta-lactamase-producing bacteria, thereby extending its spectrum of activity against resistant strains. Hexzone-SB is indicated for the management of infections caused by susceptible organisms, including lower respiratory tract infections, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, and septicemia. The injection is administered intravenously or intramuscularly, with dosage and duration tailored according to the severity of infection and patient response. It is contraindicated in patients with known hypersensitivity to cephalosporins, penicillins, or beta-lactamase inhibitors. Caution is advised in patients with renal or hepatic impairment. Adverse reactions may include hypersensitivity reactions, gastrointestinal disturbances, and local injection site reactions. Hexzone-SB 375mg Injection should be used under strict medical supervision, adhering to recommended guidelines to minimize resistance development and ensure therapeutic efficacy.
How to use Hexzone-SB Injection Your doctor or nurse will give you this medicine. Kindly do not self administer.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Consuming alcohol with Hexzone-SB 375mg Injection does not cause any harmful side effects.
High Risk
Hexzone-SB 375mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Medical Advice
Hexzone-SB 375mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Hexzone-SB 375mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Hexzone-SB 375mg Injection may be needed. Please consult your doctor. Dose adjustment of Hexzone-SB 375mg Injection is not recommended in patients with mild to moderate liver disease.
Regular Checkup
Hexzone-SB 375mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Consult Doctor
There is limited information available on the use of Hexzone-SB 375mg Injection in patients with kidney disease. Please consult your doctor.
Regular Checkup
0 reviews for Hexzone-SB 375mg Injection















