Hefcard 50 Tablet
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Strip of 14 tablets • TabletPrescription requiredSchedule H
Hefcard 50 Tablet
Sacubitril (24mg) + Valsartan (26mg)
₹315.15
Strip of 14 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
Valsartan 26 mg
+1 more active ingredient
How It Works
Valsartan blocks the action of angiotensin II at its receptor sites, leading to vasodilation and decreased blood pressure.
Sacubitril inhibits neprilysin, increasing levels of natriuretic peptides and promoting vasodilation.
Medicine Strength
26 mg
All Active Ingredients
Valsartan26 mg
Sacubitril24 mg
Uses & Benefits
Medical applications
Blood PressureHeart
Hefcard 50 Tablet contains a combination of Sacubitril (24 mg) and Valsartan (26 mg), formulated for the management of heart failure with reduced ejection fraction (HFrEF). Sacubitril is a neprilysin inhibitor that enhances the levels of natriuretic peptides, promoting vasodilation, natriuresis, and diuresis, thereby reducing cardiac workload and improving cardiac function. Valsartan, an angiotensin II receptor blocker (ARB), inhibits the effects of angiotensin II, leading to vasodilation, decreased aldosterone secretion, and reduced blood pressure.
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The synergistic action of these components helps to decrease the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure. Hefcard 50 is indicated for adult patients with symptomatic HFrEF to improve survival and quality of life. It should be administered under medical supervision with careful monitoring of blood pressure, renal function, and serum potassium levels to minimize adverse effects such as hypotension, hyperkalemia, and renal impairment.
Contraindications include a history of angioedema related to previous ACE inhibitor or ARB therapy, pregnancy, and severe hepatic impairment. Dose adjustments may be required based on patient response and tolerability.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Hefcard 50 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Pregnancy
Hefcard 50 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Driving
Hefcard 50 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Hefcard 50 Tablet may be needed. Please consult your doctor. Regular blood pressure monitoring is recommended. No dose adjustment is needed in patients with mild to moderate kidney disease.
Exercise Caution
Breastfeeding
It is not known whether Hefcard 50 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Consult Doctor
Kidney
Hefcard 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Hefcard 50 Tablet may be needed. Please consult your doctor. However, no dose adjustment is recommended in patients with mild liver disease. Hefcard 50 Tablet is contraindicated in patients with severe liver disease.
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