
Naproxen (500mg) + Sumatriptan (85mg)
Active composition
+1 more active ingredient
Naproxen inhibits COX-1 and COX-2 enzymes, decreasing the production of inflammatory mediators.
Sumatriptan binds to and activates serotonin receptors (5-HT1B and 5-HT1D) in cranial blood vessels, leading to vasoconstriction and relief from migraine symptoms.
Medical applications
Hedfree Tablet contains a combination of Sumatriptan 85 mg and Naproxen 500 mg, formulated for the acute treatment of migraine attacks with or without aura in adults. Sumatriptan, a selective serotonin 5-HT1 receptor agonist, acts by constricting intracranial blood vessels and inhibiting the release of pro-inflammatory neuropeptides, thereby alleviating migraine pain and associated symptoms such as nausea and photophobia. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), provides additional analgesic and anti-inflammatory effects by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), reducing prostaglandin synthesis responsible for pain and inflammation. The combination therapy offers synergistic benefits, improving efficacy in migraine relief compared to monotherapy with either agent. Hedfree Tablet is indicated for patients who require rapid and effective migraine symptom control. It is contraindicated in individuals with known hypersensitivity to sumatriptan, naproxen, other NSAIDs, or aspirin, as well as those with cardiovascular disease, uncontrolled hypertension, or a history of stroke. Caution is advised in patients with hepatic or renal impairment. Common adverse effects may include dizziness, nausea, dry mouth, and gastrointestinal discomfort. Patients should adhere to prescribed dosages and consult healthcare professionals for appropriate use and potential drug interactions.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Hedfree Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Hedfree Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Medical Advice
Hedfree Tablet should be used with caution in patients with kidney disease. Dose adjustment of Hedfree Tablet may be needed. Please consult your doctor.
Exercise Caution
Hedfree Tablet may cause side effects which could affect your ability to drive. Hedfree Tablet may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.
Consult Doctor
Hedfree Tablet should be used with caution in patients with liver disease. Dose adjustment of Hedfree Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Hedfree Tablet

Sumatriptan (85mg) + Naproxen (500mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Naproxen inhibits COX-1 and COX-2 enzymes, decreasing the production of inflammatory mediators.
Sumatriptan binds to and activates serotonin receptors (5-HT1B and 5-HT1D) in cranial blood vessels, leading to vasoconstriction and relief from migraine symptoms.
Medical applications
Hedfree Tablet contains a combination of Sumatriptan 85 mg and Naproxen 500 mg, formulated for the acute treatment of migraine attacks with or without aura in adults. Sumatriptan, a selective serotonin 5-HT1 receptor agonist, acts by constricting intracranial blood vessels and inhibiting the release of pro-inflammatory neuropeptides, thereby alleviating migraine pain and associated symptoms such as nausea and photophobia. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), provides additional analgesic and anti-inflammatory effects by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), reducing prostaglandin synthesis responsible for pain and inflammation. The combination therapy offers synergistic benefits, improving efficacy in migraine relief compared to monotherapy with either agent. Hedfree Tablet is indicated for patients who require rapid and effective migraine symptom control. It is contraindicated in individuals with known hypersensitivity to sumatriptan, naproxen, other NSAIDs, or aspirin, as well as those with cardiovascular disease, uncontrolled hypertension, or a history of stroke. Caution is advised in patients with hepatic or renal impairment. Common adverse effects may include dizziness, nausea, dry mouth, and gastrointestinal discomfort. Patients should adhere to prescribed dosages and consult healthcare professionals for appropriate use and potential drug interactions.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Hedfree Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Hedfree Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Medical Advice
Hedfree Tablet should be used with caution in patients with kidney disease. Dose adjustment of Hedfree Tablet may be needed. Please consult your doctor.
Exercise Caution
Hedfree Tablet may cause side effects which could affect your ability to drive. Hedfree Tablet may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.
Consult Doctor
Hedfree Tablet should be used with caution in patients with liver disease. Dose adjustment of Hedfree Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Hedfree Tablet















