Gudtel-M 25 Tablet ER is a combination antihypertensive medication containing Telmisartan 40 mg and Metoprolol Succinate 23.75 mg in an extended-release formulation. Telmisartan, an angiotensin II receptor blocker (ARB), selectively inhibits the binding of angiotensin II to the AT1 receptor, thereby reducing vasoconstriction and aldosterone secretion, which leads to decreased blood pressure and improved cardiovascular outcomes. Metoprolol Succinate, a beta-1 selective adrenergic blocker, reduces heart rate, myocardial contractility, and cardiac output, contributing to blood pressure reduction and decreased myocardial oxygen demand. The extended-release formulation ensures sustained plasma concentrations, promoting once-daily dosing and improved patient compliance. Gudtel-M 25 is indicated for the management of essential hypertension, particularly in patients requiring combination therapy to achieve optimal blood pressure control. It may also be beneficial in patients with concomitant cardiovascular conditions such as ischemic heart disease or heart failure where beta-blockade is advantageous. Caution is advised in patients with bradycardia, heart block, or severe hepatic impairment. Common adverse effects include dizziness, fatigue, and hypotension. Regular monitoring of blood pressure, renal function, and electrolytes is recommended during therapy. Gudtel-M 25 should be used under medical supervision to ensure safety and efficacy.

Dosage & How to Use

Dosage information not available. Please consult your doctor or pharmacist.