
Nitroglycerin (0.4mg)
Active composition
Nitroglycerin is converted to nitric oxide in the body, which activates guanylate cyclase, leading to increased cGMP levels and subsequent vasodilation of blood vessels.
Medical applications
GTN Spray contains Nitroglycerin 0.4 mg per actuation and is indicated for the rapid relief of angina pectoris symptoms associated with coronary artery disease. Nitroglycerin is a potent vasodilator that acts primarily on the venous system, reducing myocardial oxygen demand by decreasing preload and, to a lesser extent, afterload. This leads to improved coronary blood flow and alleviation of ischemic chest pain. GTN Spray is administered sublingually, allowing for rapid absorption and onset of action within 1 to 3 minutes, making it suitable for acute angina attacks. The spray delivers a metered dose, ensuring consistent and accurate dosing. It is recommended to use one spray under the tongue at the onset of angina symptoms; if pain persists after 5 minutes, a second dose may be administered, with a maximum of three doses within 15 minutes. Patients experiencing no relief after the third dose should seek immediate medical attention. GTN Spray should be used with caution in patients with hypotension, severe anemia, or increased intracranial pressure. Common adverse effects include headache, dizziness, and flushing. It is contraindicated in patients using phosphodiesterase inhibitors due to the risk of severe hypotension. Proper storage and adherence to prescribed dosing are essential for optimal therapeutic outcomes.
Nitrates {Short acting}
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
GTN Spray is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
High Risk
GTN Spray is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Medical Advice
GTN Spray is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of GTN Spray may not be needed in these patients. Please consult your doctor.
Exercise Caution
GTN Spray may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
There is limited information available on the use of GTN Spray in patients with liver disease. Please consult your doctor.
Regular Checkup
0 reviews for GTN Spray

Nitroglycerin (0.4mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
Nitroglycerin is converted to nitric oxide in the body, which activates guanylate cyclase, leading to increased cGMP levels and subsequent vasodilation of blood vessels.
Medical applications
GTN Spray contains Nitroglycerin 0.4 mg per actuation and is indicated for the rapid relief of angina pectoris symptoms associated with coronary artery disease. Nitroglycerin is a potent vasodilator that acts primarily on the venous system, reducing myocardial oxygen demand by decreasing preload and, to a lesser extent, afterload. This leads to improved coronary blood flow and alleviation of ischemic chest pain. GTN Spray is administered sublingually, allowing for rapid absorption and onset of action within 1 to 3 minutes, making it suitable for acute angina attacks. The spray delivers a metered dose, ensuring consistent and accurate dosing. It is recommended to use one spray under the tongue at the onset of angina symptoms; if pain persists after 5 minutes, a second dose may be administered, with a maximum of three doses within 15 minutes. Patients experiencing no relief after the third dose should seek immediate medical attention. GTN Spray should be used with caution in patients with hypotension, severe anemia, or increased intracranial pressure. Common adverse effects include headache, dizziness, and flushing. It is contraindicated in patients using phosphodiesterase inhibitors due to the risk of severe hypotension. Proper storage and adherence to prescribed dosing are essential for optimal therapeutic outcomes.
Nitrates {Short acting}
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
GTN Spray is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
High Risk
GTN Spray is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Medical Advice
GTN Spray is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of GTN Spray may not be needed in these patients. Please consult your doctor.
Exercise Caution
GTN Spray may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
There is limited information available on the use of GTN Spray in patients with liver disease. Please consult your doctor.
Regular Checkup
0 reviews for GTN Spray















