Glytrin-Met 1000 Tablet
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Metformin (1000mg) + Teneligliptin (20mg)
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Teneligliptin inhibits DPP-4, increasing incretin levels and enhancing insulin secretion.
Medical applications
Glytrin-Met 1000 Tablet is a fixed-dose combination medication containing Metformin 1000 mg and Teneligliptin 20 mg, indicated for the management of type 2 diabetes mellitus. Metformin, a biguanide, primarily acts by decreasing hepatic glucose production and improving insulin sensitivity, thereby enhancing peripheral glucose uptake and utilization. Teneligliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, increases endogenous incretin levels, which in turn stimulate insulin secretion and suppress glucagon release in a glucose-dependent manner.
The combination of these two agents provides complementary mechanisms to achieve better glycemic control in patients inadequately controlled on monotherapy or lifestyle interventions alone. Glytrin-Met 1000 Tablet is typically administered orally once or twice daily with meals to minimize gastrointestinal side effects commonly associated with Metformin. It is essential to monitor renal function prior to and during treatment, as Metformin is contraindicated in patients with significant renal impairment due to the risk of lactic acidosis.
Teneligliptin is generally well tolerated, with a low risk of hypoglycemia when used in combination with Metformin. This combination therapy should be used as part of a comprehensive diabetes management plan including diet, exercise, and regular monitoring of blood glucose levels.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Glytrin-Met 1000 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Glytrin-Met 1000 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Glytrin-Met 1000 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Glytrin-Met 1000 Tablet may be needed. Please consult your doctor. Use of Glytrin-Met 1000 Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Exercise Caution
It is not known whether Glytrin-Met 1000 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Consult Doctor
Glytrin-Met 1000 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
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