
Metformin (500mg) + Glimepiride (1mg)
Active composition
+1 more active ingredient
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
Medical applications
Glyciphage-G 1 Tablet PR contains a combination of Glimepiride (1 mg) and Metformin (500 mg), formulated for the management of type 2 diabetes mellitus. Glimepiride is a sulfonylurea class antidiabetic agent that stimulates pancreatic beta cells to release insulin, thereby lowering blood glucose levels. Metformin, a biguanide, primarily acts by decreasing hepatic glucose production and improving peripheral insulin sensitivity, contributing to enhanced glycemic control. The combination of these two agents provides a complementary mechanism of action, making Glyciphage-G effective in patients inadequately controlled by diet and exercise alone or monotherapy. This medication is indicated for adults with type 2 diabetes who require dual therapy to achieve optimal blood glucose regulation. Glyciphage-G should be used alongside lifestyle modifications such as diet and physical activity. It is important to monitor blood glucose levels regularly and adjust dosage based on therapeutic response and tolerability. Common adverse effects may include gastrointestinal disturbances, hypoglycemia, and, rarely, lactic acidosis. Caution is advised in patients with renal or hepatic impairment, and contraindications include severe renal dysfunction and conditions predisposing to hypoxia. Glyciphage-G 1 Tablet PR offers a sustained-release formulation to improve patient compliance and maintain steady plasma concentrations.
How to use Glyciphage-G Tablet PR Use it as advised by your doctor or check the label for directions before use. Glyciphage-G 1 Tablet PR is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Glyciphage-G 1 Tablet PR.
High Risk
Glyciphage-G 1 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Glyciphage-G 1 Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Glyciphage-G 1 Tablet PR may be needed. Please consult your doctor. Glyciphage-G 1 Tablet PR is generally started with a low dose in patients with mild to moderate liver disease, and its use is not recommended in patients with severe liver disease.
Regular Checkup
Glyciphage-G 1 Tablet PR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Glyciphage-G 1 Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Glyciphage-G 1 Tablet PR may be needed. Please consult your doctor. Use of Glyciphage-G 1 Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Regular Checkup
0 reviews for Glyciphage-G 1 Tablet PR

Glimepiride (1mg) + Metformin (500mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
Medical applications
Glyciphage-G 1 Tablet PR contains a combination of Glimepiride (1 mg) and Metformin (500 mg), formulated for the management of type 2 diabetes mellitus. Glimepiride is a sulfonylurea class antidiabetic agent that stimulates pancreatic beta cells to release insulin, thereby lowering blood glucose levels. Metformin, a biguanide, primarily acts by decreasing hepatic glucose production and improving peripheral insulin sensitivity, contributing to enhanced glycemic control. The combination of these two agents provides a complementary mechanism of action, making Glyciphage-G effective in patients inadequately controlled by diet and exercise alone or monotherapy. This medication is indicated for adults with type 2 diabetes who require dual therapy to achieve optimal blood glucose regulation. Glyciphage-G should be used alongside lifestyle modifications such as diet and physical activity. It is important to monitor blood glucose levels regularly and adjust dosage based on therapeutic response and tolerability. Common adverse effects may include gastrointestinal disturbances, hypoglycemia, and, rarely, lactic acidosis. Caution is advised in patients with renal or hepatic impairment, and contraindications include severe renal dysfunction and conditions predisposing to hypoxia. Glyciphage-G 1 Tablet PR offers a sustained-release formulation to improve patient compliance and maintain steady plasma concentrations.
How to use Glyciphage-G Tablet PR Use it as advised by your doctor or check the label for directions before use. Glyciphage-G 1 Tablet PR is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Glyciphage-G 1 Tablet PR.
High Risk
Glyciphage-G 1 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Glyciphage-G 1 Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Glyciphage-G 1 Tablet PR may be needed. Please consult your doctor. Glyciphage-G 1 Tablet PR is generally started with a low dose in patients with mild to moderate liver disease, and its use is not recommended in patients with severe liver disease.
Regular Checkup
Glyciphage-G 1 Tablet PR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Glyciphage-G 1 Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Glyciphage-G 1 Tablet PR may be needed. Please consult your doctor. Use of Glyciphage-G 1 Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Regular Checkup
0 reviews for Glyciphage-G 1 Tablet PR













