Glimestar-M2 Forte Tablet PR
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Glimepiride (2mg) + Metformin (1000mg)
1 units • Other
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Medical applications
Glimestar-M2 Forte Tablet PR is a combination oral antihyperglycemic agent containing Glimepiride (2mg) and Metformin (1000mg), indicated for the management of type 2 diabetes mellitus. Glimepiride, a sulfonylurea class drug, stimulates pancreatic beta cells to release insulin, thereby improving glycemic control. Metformin, a biguanide, primarily acts by decreasing hepatic glucose production, enhancing peripheral glucose uptake, and improving insulin sensitivity.
This dual mechanism addresses both insulin secretion and insulin resistance, making Glimestar-M2 Forte effective in achieving optimal blood glucose levels in patients inadequately controlled by diet and exercise alone. The prolonged-release formulation ensures a steady plasma concentration, reducing the risk of hypoglycemia and gastrointestinal side effects commonly associated with immediate-release metformin.
Glimestar-M2 Forte should be administered once daily with meals to enhance absorption and minimize gastrointestinal discomfort. It is contraindicated in patients with renal impairment, hepatic dysfunction, or conditions predisposing to lactic acidosis. Regular monitoring of blood glucose, renal function, and lactic acid levels is recommended during therapy. This combination therapy should be used as part of a comprehensive diabetes management plan, including diet, exercise, and weight control, to reduce the risk of diabetes-related complications.
How to use Glimestar-M Tablet PR Use it as advised by your doctor or check the label for directions before use. Glimestar-M2 Forte Tablet PR is to be taken with food.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
It is unsafe to consume alcohol with Glimestar-M2 Forte Tablet PR.
High Risk
Glimestar-M2 Forte Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Glimestar-M2 Forte Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Glimestar-M2 Forte Tablet PR may be needed. Please consult your doctor. Glimestar-M2 Forte Tablet PR is generally started with a low dose in patients with mild to moderate liver disease, and its use is not recommended in patients with severe liver disease.
Regular Checkup
Glimestar-M2 Forte Tablet PR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Glimestar-M2 Forte Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Glimestar-M2 Forte Tablet PR may be needed. Please consult your doctor. Use of Glimestar-M2 Forte Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Regular Checkup
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