
Glimepiride (1mg) + Metformin (500mg)
Active composition
+1 more active ingredient
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Medical applications
Glimestar-M 1 Tablet PR contains a combination of Glimepiride 1 mg and Metformin 500 mg, formulated for the management of type 2 diabetes mellitus. Glimepiride, a sulfonylurea class agent, stimulates pancreatic beta cells to enhance insulin secretion, thereby reducing blood glucose levels. Metformin, a biguanide, primarily decreases hepatic glucose production and improves peripheral insulin sensitivity, contributing to better glycemic control. This combination is indicated for patients whose blood glucose levels are inadequately controlled by diet, exercise, and monotherapy with either agent alone. Glimestar-M 1 Tablet PR is designed for prolonged release, allowing for sustained therapeutic effects and improved patient compliance through once-daily dosing. It is essential to monitor renal function prior to and during treatment, as Metformin is contraindicated in patients with significant renal impairment due to the risk of lactic acidosis. Common adverse effects may include gastrointestinal disturbances such as nausea, diarrhea, and abdominal discomfort, which often subside with continued use. Hypoglycemia is a potential risk, primarily attributable to Glimepiride, necessitating patient education on recognizing and managing low blood sugar episodes. Glimestar-M 1 Tablet PR should be used as part of a comprehensive diabetes management plan including diet, exercise, and regular monitoring of blood glucose levels.
How to use Glimestar-M Tablet PR Use it as advised by your doctor or check the label for directions before use. Glimestar-M 1 Tablet PR is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Glimestar-M 1 Tablet PR.
High Risk
Glimestar-M 1 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Glimestar-M 1 Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Glimestar-M 1 Tablet PR may be needed. Please consult your doctor. Glimestar-M 1 Tablet PR is generally started with a low dose in patients with mild to moderate liver disease, and its use is not recommended in patients with severe liver disease.
Regular Checkup
Glimestar-M 1 Tablet PR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Glimestar-M 1 Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Glimestar-M 1 Tablet PR may be needed. Please consult your doctor. Use of Glimestar-M 1 Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Regular Checkup
0 reviews for Glimestar-M 1 Tablet PR

Glimepiride (1mg) + Metformin (500mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Medical applications
Glimestar-M 1 Tablet PR contains a combination of Glimepiride 1 mg and Metformin 500 mg, formulated for the management of type 2 diabetes mellitus. Glimepiride, a sulfonylurea class agent, stimulates pancreatic beta cells to enhance insulin secretion, thereby reducing blood glucose levels. Metformin, a biguanide, primarily decreases hepatic glucose production and improves peripheral insulin sensitivity, contributing to better glycemic control. This combination is indicated for patients whose blood glucose levels are inadequately controlled by diet, exercise, and monotherapy with either agent alone. Glimestar-M 1 Tablet PR is designed for prolonged release, allowing for sustained therapeutic effects and improved patient compliance through once-daily dosing. It is essential to monitor renal function prior to and during treatment, as Metformin is contraindicated in patients with significant renal impairment due to the risk of lactic acidosis. Common adverse effects may include gastrointestinal disturbances such as nausea, diarrhea, and abdominal discomfort, which often subside with continued use. Hypoglycemia is a potential risk, primarily attributable to Glimepiride, necessitating patient education on recognizing and managing low blood sugar episodes. Glimestar-M 1 Tablet PR should be used as part of a comprehensive diabetes management plan including diet, exercise, and regular monitoring of blood glucose levels.
How to use Glimestar-M Tablet PR Use it as advised by your doctor or check the label for directions before use. Glimestar-M 1 Tablet PR is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Glimestar-M 1 Tablet PR.
High Risk
Glimestar-M 1 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Glimestar-M 1 Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Glimestar-M 1 Tablet PR may be needed. Please consult your doctor. Glimestar-M 1 Tablet PR is generally started with a low dose in patients with mild to moderate liver disease, and its use is not recommended in patients with severe liver disease.
Regular Checkup
Glimestar-M 1 Tablet PR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Glimestar-M 1 Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Glimestar-M 1 Tablet PR may be needed. Please consult your doctor. Use of Glimestar-M 1 Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Regular Checkup
0 reviews for Glimestar-M 1 Tablet PR













