Glidimin PM 2 Tablet SR
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1 units • OtherPrescription requiredSchedule H
Glidimin PM 2 Tablet SR
Glimepiride (2mg) + Metformin (500mg) + Pioglitazone (15mg)
₹225.00
1 units • Other
A valid prescription is required for this medicine.
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Active composition
Pioglitazone 15 mg
+2 more active ingredients
How It Works
Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-γ), enhancing insulin sensitivity and glucose metabolism.
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
Medicine Strength
15 mg
All Active Ingredients
Pioglitazone15 mg
Metformin500 mg
Glimepiride2 mg
Uses & Benefits
Medical applications
Diabetes
Glidimin PM 2 Tablet SR is a combination oral hypoglycemic agent formulated for the management of type 2 diabetes mellitus. Each sustained-release tablet contains Glimepiride 2 mg, Metformin 500 mg, and Pioglitazone 15 mg, providing a multifaceted approach to glycemic control. Glimepiride, a sulfonylurea, stimulates pancreatic beta-cell insulin secretion, thereby enhancing endogenous insulin levels.
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Metformin, a biguanide, primarily acts by decreasing hepatic glucose production and improving peripheral insulin sensitivity, contributing to better glucose uptake in muscle tissues. Pioglitazone, a thiazolidinedione, further enhances insulin sensitivity by activating peroxisome proliferator-activated receptor gamma (PPAR-γ), leading to improved glucose utilization and lipid metabolism.
The sustained-release formulation ensures gradual drug release, promoting stable plasma concentrations and reducing gastrointestinal side effects commonly associated with Metformin. Glidimin PM 2 is indicated for patients inadequately controlled on monotherapy or dual therapy, offering improved glycemic control through complementary mechanisms. It should be used alongside diet and exercise for optimal efficacy.
Caution is advised in patients with hepatic, renal, or cardiac impairment, and regular monitoring of blood glucose, liver function, and hematologic parameters is recommended. This combination therapy facilitates comprehensive management of hyperglycemia, aiming to reduce the risk of diabetes-related complications.
Dosage & How to Use
How to use Glidimin PM Tablet SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glidimin PM 2 Tablet SR is to be taken with food.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
It is unsafe to consume alcohol with Glidimin PM 2 Tablet SR.
High Risk
Pregnancy
Glidimin PM 2 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Driving
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Liver
Glidimin PM 2 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Glidimin PM 2 Tablet SR may be needed. Please consult your doctor. Use of Glidimin PM 2 Tablet SR is not recommended in patients with severe liver disease.
Regular Checkup
Breastfeeding
Glidimin PM 2 Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Kidney
Glidimin PM 2 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Glidimin PM 2 Tablet SR may be needed. Please consult your doctor. Use of Glidimin PM 2 Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Regular Checkup
Customer Reviews
0 reviews for Glidimin PM 2 Tablet SR
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