
Metformin (500mg) + Gliclazide (80mg)
Active composition
+1 more active ingredient
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Gliclazide stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues.
Medical applications
Gli-M Tablet is a combination oral hypoglycemic agent containing Gliclazide 80 mg and Metformin 500 mg, indicated for the management of type 2 diabetes mellitus. Gliclazide, a sulfonylurea class drug, stimulates pancreatic beta cells to enhance insulin secretion, thereby improving glycemic control. Metformin, a biguanide, primarily acts by decreasing hepatic glucose production and improving peripheral insulin sensitivity, which helps reduce blood glucose levels without causing significant hypoglycemia. The synergistic action of these two agents provides effective glycemic regulation in patients inadequately controlled by diet and exercise alone. Gli-M Tablet is typically prescribed as part of a comprehensive diabetes management plan that includes lifestyle modifications such as diet and physical activity. It is contraindicated in patients with severe renal or hepatic impairment, diabetic ketoacidosis, or hypersensitivity to either component. Common adverse effects may include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal discomfort, which often subside with continued use. Regular monitoring of blood glucose, renal function, and liver enzymes is recommended during therapy. Gli-M Tablet should be used under medical supervision to optimize therapeutic outcomes and minimize potential risks.
How to use Gli-M Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gli-M Tablet is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Gli-M Tablet.
High Risk
Gli-M Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Gli-M Tablet should be used with caution in patients with liver disease. Dose adjustment of Gli-M Tablet may be needed. Please consult your doctor. Gli-M Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
Regular Checkup
Gli-M Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Gli-M Tablet should be used with caution in patients with kidney disease. Dose adjustment of Gli-M Tablet may be needed. Please consult your doctor. Use of Gli-M Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Regular Checkup
0 reviews for Gli-M Tablet

Gliclazide (80mg) + Metformin (500mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Gliclazide stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues.
Medical applications
Gli-M Tablet is a combination oral hypoglycemic agent containing Gliclazide 80 mg and Metformin 500 mg, indicated for the management of type 2 diabetes mellitus. Gliclazide, a sulfonylurea class drug, stimulates pancreatic beta cells to enhance insulin secretion, thereby improving glycemic control. Metformin, a biguanide, primarily acts by decreasing hepatic glucose production and improving peripheral insulin sensitivity, which helps reduce blood glucose levels without causing significant hypoglycemia. The synergistic action of these two agents provides effective glycemic regulation in patients inadequately controlled by diet and exercise alone. Gli-M Tablet is typically prescribed as part of a comprehensive diabetes management plan that includes lifestyle modifications such as diet and physical activity. It is contraindicated in patients with severe renal or hepatic impairment, diabetic ketoacidosis, or hypersensitivity to either component. Common adverse effects may include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal discomfort, which often subside with continued use. Regular monitoring of blood glucose, renal function, and liver enzymes is recommended during therapy. Gli-M Tablet should be used under medical supervision to optimize therapeutic outcomes and minimize potential risks.
How to use Gli-M Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gli-M Tablet is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Gli-M Tablet.
High Risk
Gli-M Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Gli-M Tablet should be used with caution in patients with liver disease. Dose adjustment of Gli-M Tablet may be needed. Please consult your doctor. Gli-M Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
Regular Checkup
Gli-M Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Gli-M Tablet should be used with caution in patients with kidney disease. Dose adjustment of Gli-M Tablet may be needed. Please consult your doctor. Use of Gli-M Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Regular Checkup
0 reviews for Gli-M Tablet













