
Ofloxacin (0.75% w/w) + Ornidazole (2% w/w) + Clobetasol (0.05% w/w) + Itraconazole (1% w/w)
Active composition
+3 more active ingredients
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Ornidazole disrupts DNA synthesis in protozoan organisms, leading to cell death and resolution of infection.
Clobetasol binds to glucocorticoid receptors, inhibiting the transcription of pro-inflammatory genes and reducing inflammation.
Itraconazole inhibits the synthesis of ergosterol, disrupting fungal cell membrane integrity.
Medical applications
Gilderm Plus Cream is a topical formulation combining Ofloxacin (0.75% w/w), Ornidazole (2% w/w), Itraconazole (1% w/w), and Clobetasol (0.05% w/w) designed for the effective management of mixed bacterial, protozoal, fungal infections, and inflammatory dermatoses. Ofloxacin, a broad-spectrum fluoroquinolone antibiotic, targets susceptible Gram-positive and Gram-negative bacteria by inhibiting DNA gyrase, thereby preventing bacterial replication. Ornidazole, a nitroimidazole derivative, exhibits potent activity against anaerobic protozoa and bacteria by disrupting DNA synthesis. Itraconazole, a triazole antifungal agent, inhibits ergosterol synthesis essential for fungal cell membrane integrity, providing broad antifungal coverage. Clobetasol propionate, a super potent corticosteroid, exerts anti-inflammatory, antipruritic, and vasoconstrictive effects, reducing inflammation and immune response in affected skin areas. The combination therapy is indicated for dermatological conditions involving mixed infections where inflammation is prominent, such as complicated dermatoses, infected eczema, and certain fungal-bacterial co-infections. Gilderm Plus Cream should be applied topically as directed by a healthcare professional, avoiding prolonged use to minimize potential adverse effects associated with potent corticosteroids, including skin atrophy and systemic absorption. Contraindications include hypersensitivity to any component and viral skin infections. Use under medical supervision is recommended to ensure appropriate diagnosis and treatment monitoring.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Information regarding the use of Gilderm Plus Cream during pregnancy is not available. Please consult your doctor.
High Risk
Information regarding the use of Gilderm Plus Cream during breastfeeding is not available. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
No interaction found/established
Consult Doctor
No interaction found/established
Regular Checkup
0 reviews for Gilderm Plus Cream

Ofloxacin (0.75% w/w) + Ornidazole (2% w/w) + Itraconazole (1% w/w) + Clobetasol (0.05% w/w)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+3 more active ingredients
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Ornidazole disrupts DNA synthesis in protozoan organisms, leading to cell death and resolution of infection.
Clobetasol binds to glucocorticoid receptors, inhibiting the transcription of pro-inflammatory genes and reducing inflammation.
Itraconazole inhibits the synthesis of ergosterol, disrupting fungal cell membrane integrity.
Medical applications
Gilderm Plus Cream is a topical formulation combining Ofloxacin (0.75% w/w), Ornidazole (2% w/w), Itraconazole (1% w/w), and Clobetasol (0.05% w/w) designed for the effective management of mixed bacterial, protozoal, fungal infections, and inflammatory dermatoses. Ofloxacin, a broad-spectrum fluoroquinolone antibiotic, targets susceptible Gram-positive and Gram-negative bacteria by inhibiting DNA gyrase, thereby preventing bacterial replication. Ornidazole, a nitroimidazole derivative, exhibits potent activity against anaerobic protozoa and bacteria by disrupting DNA synthesis. Itraconazole, a triazole antifungal agent, inhibits ergosterol synthesis essential for fungal cell membrane integrity, providing broad antifungal coverage. Clobetasol propionate, a super potent corticosteroid, exerts anti-inflammatory, antipruritic, and vasoconstrictive effects, reducing inflammation and immune response in affected skin areas. The combination therapy is indicated for dermatological conditions involving mixed infections where inflammation is prominent, such as complicated dermatoses, infected eczema, and certain fungal-bacterial co-infections. Gilderm Plus Cream should be applied topically as directed by a healthcare professional, avoiding prolonged use to minimize potential adverse effects associated with potent corticosteroids, including skin atrophy and systemic absorption. Contraindications include hypersensitivity to any component and viral skin infections. Use under medical supervision is recommended to ensure appropriate diagnosis and treatment monitoring.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Information regarding the use of Gilderm Plus Cream during pregnancy is not available. Please consult your doctor.
High Risk
Information regarding the use of Gilderm Plus Cream during breastfeeding is not available. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
No interaction found/established
Consult Doctor
No interaction found/established
Regular Checkup
0 reviews for Gilderm Plus Cream















