
Paracetamol (325mg) + Flupirtine (100mg)
Active composition
+1 more active ingredient
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Flupirtine acts on the central nervous system to inhibit pain perception and relax muscles.
Medical applications
Flupinex Plus 100mg/325mg Tablet is a combination analgesic medication containing Flupirtine 100mg and Paracetamol 325mg, designed to provide effective relief from moderate to severe pain. Flupirtine acts as a non-opioid muscle relaxant and analgesic by modulating neuronal potassium channels, thereby reducing nerve excitability and alleviating pain without the typical side effects associated with opioids. Paracetamol, a widely used analgesic and antipyretic, works by inhibiting prostaglandin synthesis in the central nervous system, helping to reduce pain and fever. The synergistic effect of these two active ingredients makes Flupinex Plus suitable for managing conditions such as musculoskeletal pain, postoperative pain, and other acute pain states. This combination offers rapid onset of action and sustained pain relief, improving patient comfort and mobility. Flupinex Plus should be used under medical supervision, with attention to dosage limits to avoid potential hepatotoxicity from Paracetamol and contraindications related to Flupirtine, including liver function monitoring. It is not recommended for long-term use due to possible adverse effects. Patients should inform their healthcare provider of any existing medical conditions or concurrent medications before starting treatment with Flupinex Plus.
How to use Flupinex Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Flupinex Plus 100mg/325mg Tablet is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Flupinex Plus 100mg/325mg Tablet.
High Risk
Flupinex Plus 100mg/325mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
It is not known whether Flupinex Plus 100mg/325mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Exercise Caution
Flupinex Plus 100mg/325mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Flupinex Plus 100mg/325mg Tablet may be needed. Please consult your doctor. However, the use of Flupinex Plus 100mg/325mg Tablet is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
Information regarding the use of Flupinex Plus 100mg/325mg Tablet during breastfeeding is not available. Please consult your doctor.
Consult Doctor
Flupinex Plus 100mg/325mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Flupinex Plus 100mg/325mg Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Flupinex Plus 100mg/325mg Tablet

Flupirtine (100mg) + Paracetamol (325mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Flupirtine acts on the central nervous system to inhibit pain perception and relax muscles.
Medical applications
Flupinex Plus 100mg/325mg Tablet is a combination analgesic medication containing Flupirtine 100mg and Paracetamol 325mg, designed to provide effective relief from moderate to severe pain. Flupirtine acts as a non-opioid muscle relaxant and analgesic by modulating neuronal potassium channels, thereby reducing nerve excitability and alleviating pain without the typical side effects associated with opioids. Paracetamol, a widely used analgesic and antipyretic, works by inhibiting prostaglandin synthesis in the central nervous system, helping to reduce pain and fever. The synergistic effect of these two active ingredients makes Flupinex Plus suitable for managing conditions such as musculoskeletal pain, postoperative pain, and other acute pain states. This combination offers rapid onset of action and sustained pain relief, improving patient comfort and mobility. Flupinex Plus should be used under medical supervision, with attention to dosage limits to avoid potential hepatotoxicity from Paracetamol and contraindications related to Flupirtine, including liver function monitoring. It is not recommended for long-term use due to possible adverse effects. Patients should inform their healthcare provider of any existing medical conditions or concurrent medications before starting treatment with Flupinex Plus.
How to use Flupinex Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Flupinex Plus 100mg/325mg Tablet is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Flupinex Plus 100mg/325mg Tablet.
High Risk
Flupinex Plus 100mg/325mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
It is not known whether Flupinex Plus 100mg/325mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Exercise Caution
Flupinex Plus 100mg/325mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Flupinex Plus 100mg/325mg Tablet may be needed. Please consult your doctor. However, the use of Flupinex Plus 100mg/325mg Tablet is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
Information regarding the use of Flupinex Plus 100mg/325mg Tablet during breastfeeding is not available. Please consult your doctor.
Consult Doctor
Flupinex Plus 100mg/325mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Flupinex Plus 100mg/325mg Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Flupinex Plus 100mg/325mg Tablet











