Esomac HP 750mg/500mg/40mg Combo Kit
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Packet of 6 tablets • TabletPrescription requiredSchedule H
Esomac HP 750mg/500mg/40mg Combo Kit
Amoxycillin (750mg) + Clarithromycin (500mg) + Esomeprazole (40mg)
₹209.62
Packet of 6 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
Esomeprazole 40 mg
+2 more active ingredients
How It Works
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Amoxycillin inhibits the synthesis of peptidoglycan in bacterial cell walls, leading to cell lysis and death.
Clarithromycin binds to the 50S ribosomal subunit, inhibiting bacterial protein synthesis and growth.
Medicine Strength
40 mg
All Active Ingredients
Esomeprazole40 mg
Amoxycillin750 mg
Clarithromycin500 mg
Uses & Benefits
Medical applications
InfectionBacterialUlcerNausea
Esomac HP 750mg/500mg/40mg Combo Kit is a combination therapy comprising Amoxycillin 750mg, Clarithromycin 500mg, and Esomeprazole 40mg, indicated primarily for the eradication of Helicobacter pylori infection associated with peptic ulcer disease and gastritis. Amoxycillin, a broad-spectrum beta-lactam antibiotic, acts by inhibiting bacterial cell wall synthesis, leading to bacterial cell death.
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Clarithromycin, a macrolide antibiotic, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, providing synergistic antibacterial activity against H. pylori. Esomeprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme in gastric parietal cells, creating a less acidic environment that enhances antibiotic efficacy and promotes mucosal healing.
This triple therapy is typically administered for 7 to 14 days to achieve optimal eradication rates. It is essential to adhere to the prescribed dosage and duration to prevent antibiotic resistance and ensure treatment success. Common adverse effects may include gastrointestinal disturbances such as nausea, diarrhea, and abdominal discomfort. Caution is advised in patients with known hypersensitivity to any component, liver impairment, or concurrent use of interacting medications.
Consultation with a healthcare professional is recommended before initiating therapy.
Dosage & How to Use
How to use Esomac HP Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esomac HP 750mg/500mg/40mg Combo Kit is to be taken empty stomach.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Caution is advised when consuming alcohol with Esomac HP 750mg/500mg/40mg Combo Kit. Please consult your doctor.
High Risk
Pregnancy
Esomac HP 750mg/500mg/40mg Combo Kit may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Driving
Esomac HP 750mg/500mg/40mg Combo Kit may cause side effects which could affect your ability to drive. Esomac HP 750mg/500mg/40mg Combo Kit can have side effects and the symptoms (such as allergic reactions, dizziness and convulsions) may make you unfit to drive.
Exercise Caution
Liver
Esomac HP 750mg/500mg/40mg Combo Kit is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Esomac HP 750mg/500mg/40mg Combo Kit may not be needed in these patients. Please consult your doctor.
Regular Checkup
Breastfeeding
Esomac HP 750mg/500mg/40mg Combo Kit is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Kidney
Esomac HP 750mg/500mg/40mg Combo Kit should be used with caution in patients with kidney disease. Dose adjustment of Esomac HP 750mg/500mg/40mg Combo Kit may be needed. Please consult your doctor.
Regular Checkup
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