
Epalrestat (150mg) + Methylcobalamin (1500mcg)
Active composition
+1 more active ingredient
Epalrestat inhibits aldose reductase, reducing sorbitol accumulation and preventing nerve damage in diabetic patients.
Methylcobalamin acts as a cofactor in the synthesis of methionine from homocysteine, promoting nerve health and red blood cell formation.
Medical applications
Epineuron SR Tablet is a combination pharmaceutical formulation containing Epalrestat 150 mg and Methylcobalamin 1500 mcg, designed for the management of diabetic neuropathy and related peripheral nerve disorders. Epalrestat, an aldose reductase inhibitor, acts by preventing the accumulation of sorbitol in nerve tissues, thereby reducing oxidative stress and improving nerve function. Methylcobalamin, an active form of vitamin B12, supports nerve regeneration and repair by promoting myelin sheath synthesis and enhancing neuronal metabolism. The sustained-release (SR) formulation ensures a controlled and prolonged release of active ingredients, optimizing therapeutic efficacy and improving patient compliance by reducing dosing frequency. Epineuron SR is indicated for patients experiencing symptoms such as numbness, tingling, burning sensations, and pain associated with diabetic peripheral neuropathy. Clinical studies have demonstrated that the combination effectively alleviates neuropathic symptoms, improves nerve conduction velocity, and enhances quality of life. The medication should be administered under medical supervision, with dosage adjustments based on clinical response and renal function. Common side effects may include gastrointestinal discomfort and allergic reactions, which should be promptly reported to a healthcare provider. Epineuron SR Tablet represents a comprehensive approach to neuropathic pain management by combining neuroprotective and neurotrophic mechanisms.
How to use Epineuron Tablet SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epineuron SR Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Epineuron SR Tablet.
High Risk
Epineuron SR Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
It is not known whether Epineuron SR Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Exercise Caution
There is limited information available on the use of Epineuron SR Tablet in patients with liver disease. Please consult your doctor.
Regular Checkup
Information regarding the use of Epineuron SR Tablet during breastfeeding is not available. Please consult your doctor.
Consult Doctor
There is limited information available on the use of Epineuron SR Tablet in patients with kidney disease. Please consult your doctor.
Regular Checkup
0 reviews for Epineuron SR Tablet

Epalrestat (150mg) + Methylcobalamin (1500mcg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Epalrestat inhibits aldose reductase, reducing sorbitol accumulation and preventing nerve damage in diabetic patients.
Methylcobalamin acts as a cofactor in the synthesis of methionine from homocysteine, promoting nerve health and red blood cell formation.
Medical applications
Epineuron SR Tablet is a combination pharmaceutical formulation containing Epalrestat 150 mg and Methylcobalamin 1500 mcg, designed for the management of diabetic neuropathy and related peripheral nerve disorders. Epalrestat, an aldose reductase inhibitor, acts by preventing the accumulation of sorbitol in nerve tissues, thereby reducing oxidative stress and improving nerve function. Methylcobalamin, an active form of vitamin B12, supports nerve regeneration and repair by promoting myelin sheath synthesis and enhancing neuronal metabolism. The sustained-release (SR) formulation ensures a controlled and prolonged release of active ingredients, optimizing therapeutic efficacy and improving patient compliance by reducing dosing frequency. Epineuron SR is indicated for patients experiencing symptoms such as numbness, tingling, burning sensations, and pain associated with diabetic peripheral neuropathy. Clinical studies have demonstrated that the combination effectively alleviates neuropathic symptoms, improves nerve conduction velocity, and enhances quality of life. The medication should be administered under medical supervision, with dosage adjustments based on clinical response and renal function. Common side effects may include gastrointestinal discomfort and allergic reactions, which should be promptly reported to a healthcare provider. Epineuron SR Tablet represents a comprehensive approach to neuropathic pain management by combining neuroprotective and neurotrophic mechanisms.
How to use Epineuron Tablet SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epineuron SR Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Epineuron SR Tablet.
High Risk
Epineuron SR Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
It is not known whether Epineuron SR Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Exercise Caution
There is limited information available on the use of Epineuron SR Tablet in patients with liver disease. Please consult your doctor.
Regular Checkup
Information regarding the use of Epineuron SR Tablet during breastfeeding is not available. Please consult your doctor.
Consult Doctor
There is limited information available on the use of Epineuron SR Tablet in patients with kidney disease. Please consult your doctor.
Regular Checkup
0 reviews for Epineuron SR Tablet















