Epalrica-M Tablet SR
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Epalrestat (150mg) + Methylcobalamin (1500mcg)
1 units • Other
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Methylcobalamin acts as a cofactor in the synthesis of methionine from homocysteine, promoting nerve health and red blood cell formation.
Epalrestat inhibits aldose reductase, reducing sorbitol accumulation and preventing nerve damage in diabetic patients.
Medical applications
Epalrica-M Tablet SR is a sustained-release formulation combining Epalrestat 150 mg and Methylcobalamin 1500 mcg, designed for the management of diabetic neuropathy. Epalrestat, an aldose reductase inhibitor, acts by preventing the accumulation of sorbitol in nerve tissues, thereby reducing osmotic and oxidative stress associated with hyperglycemia-induced nerve damage. This mechanism helps in alleviating symptoms such as numbness, tingling, and burning sensations commonly experienced in diabetic peripheral neuropathy.
Methylcobalamin, an active form of vitamin B12, supports nerve regeneration and repair by promoting myelin sheath synthesis and enhancing neuronal metabolism. The sustained-release property of the tablet ensures prolonged therapeutic plasma concentrations, improving patient compliance and efficacy. Epalrica-M is indicated for patients with diabetic neuropathy to improve nerve function and reduce neuropathic pain.
It should be administered under medical supervision, with dosage adjustments based on clinical response and tolerability. Common adverse effects are generally mild and may include gastrointestinal discomfort or allergic reactions. Caution is advised in patients with renal impairment or hypersensitivity to any component. Regular monitoring of blood glucose and neurological status is recommended during therapy to optimize outcomes and minimize potential risks.
How to use Epalrica-M Tablet SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epalrica-M Tablet SR may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
It is unsafe to consume alcohol with Epalrica-M Tablet SR.
High Risk
Epalrica-M Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
It is not known whether Epalrica-M Tablet SR alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Exercise Caution
There is limited information available on the use of Epalrica-M Tablet SR in patients with liver disease. Please consult your doctor.
Regular Checkup
Information regarding the use of Epalrica-M Tablet SR during breastfeeding is not available. Please consult your doctor.
Consult Doctor
There is limited information available on the use of Epalrica-M Tablet SR in patients with kidney disease. Please consult your doctor.
Regular Checkup
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