Topotecan is an anti-cancer medication used primarily for treating ovarian and small cell lung cancer. It works by inhibiting topoisomerase I, an enzyme crucial for DNA replication in cancer cells. By preventing DNA unwinding, Topotecan effectively halts cancer cell growth and induces apoptosis. In summary, it is an important therapeutic option for specific malignancies.
Topotecan inhibits topoisomerase I, preventing DNA strand relaxation and replication, leading to cancer cell death.
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