Aztreonam is a monobactam antibiotic used to treat serious bacterial infections, particularly those caused by Gram-negative bacteria. It works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Aztreonam's clinical relevance lies in its effectiveness against specific resistant bacteria and its role in managing infections in patients with allergies to other antibiotics. In summary, Aztreonam is a targeted antibiotic option for treating Gram-negative bacterial infections.
Aztreonam inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, resulting in cell lysis.