Wagtin-NT Tablet
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Gabapentin (400mg) + Nortriptyline (10mg)
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Nortriptyline inhibits the reuptake of norepinephrine and serotonin, increasing their levels in the synaptic cleft and enhancing mood.
Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Medical applications
Wagtin-NT Tablet is a combination medication containing Gabapentin 400 mg and Nortriptyline 10 mg, formulated for the management of neuropathic pain and certain chronic pain conditions. Gabapentin, an anticonvulsant, modulates neuronal excitability by binding to voltage-gated calcium channels, thereby reducing abnormal nerve signaling associated with neuropathic pain. Nortriptyline, a tricyclic antidepressant, enhances pain relief through inhibition of norepinephrine and serotonin reuptake, contributing to its analgesic and mood-stabilizing effects.
The synergistic action of these two agents provides effective pain control, particularly in cases resistant to monotherapy. Wagtin-NT is indicated for conditions such as diabetic neuropathy, postherpetic neuralgia, and other peripheral neuropathies. Dosage should be individualized based on patient response and tolerability, with careful titration to minimize adverse effects. Common side effects may include dizziness, drowsiness, dry mouth, and gastrointestinal disturbances.
Caution is advised in patients with a history of cardiac arrhythmias, glaucoma, or renal impairment. Wagtin-NT should be used under medical supervision, and abrupt discontinuation should be avoided to prevent withdrawal symptoms. This combination offers a comprehensive approach to neuropathic pain management, improving patient quality of life through multimodal analgesia.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Safety information not available for this product. Please consult your doctor or pharmacist.
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