
Olanzapine (5mg) + Fluoxetine (20mg)
Active composition
+1 more active ingredient
Olanzapine antagonizes dopamine D2 and serotonin 5-HT2A receptors, modulating neurotransmitter activity and improving mood.
Fluoxetine inhibits the reuptake of serotonin at the synaptic cleft, increasing its availability and enhancing mood regulation.
Medical applications
Olay Plus Tablet contains a combination of Fluoxetine 20mg and Olanzapine 5mg, formulated for the treatment of major depressive disorder with psychotic features and treatment-resistant depression. Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), works by increasing serotonin levels in the brain, thereby improving mood, sleep, appetite, and energy levels while reducing anxiety and depressive symptoms. Olanzapine, an atypical antipsychotic, modulates the activity of dopamine and serotonin receptors, helping to alleviate psychotic symptoms such as hallucinations, delusions, and mood disturbances. The combination of these agents provides a synergistic effect, addressing both the depressive and psychotic components of the disorder. Olay Plus is indicated for patients who have not responded adequately to antidepressant therapy alone. It should be administered under strict medical supervision, with dosage adjustments based on clinical response and tolerability. Common side effects may include weight gain, sedation, dry mouth, dizziness, and gastrointestinal disturbances. Caution is advised in patients with a history of cardiovascular disease, diabetes, or seizures. Regular monitoring of metabolic parameters and mental status is recommended during treatment. Olay Plus should not be discontinued abruptly to avoid withdrawal symptoms.
How to use Olay Plus Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Olay Plus Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Olay Plus Tablet.
High Risk
Olay Plus Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Olay Plus Tablet may cause side effects which could affect your ability to drive.
Exercise Caution
Olay Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Olay Plus Tablet may be needed. Please consult your doctor.
Regular Checkup
Olay Plus Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Olay Plus Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Olay Plus Tablet may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Olay Plus Tablet

Fluoxetine (20mg) + Olanzapine (5mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Olanzapine antagonizes dopamine D2 and serotonin 5-HT2A receptors, modulating neurotransmitter activity and improving mood.
Fluoxetine inhibits the reuptake of serotonin at the synaptic cleft, increasing its availability and enhancing mood regulation.
Medical applications
Olay Plus Tablet contains a combination of Fluoxetine 20mg and Olanzapine 5mg, formulated for the treatment of major depressive disorder with psychotic features and treatment-resistant depression. Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), works by increasing serotonin levels in the brain, thereby improving mood, sleep, appetite, and energy levels while reducing anxiety and depressive symptoms. Olanzapine, an atypical antipsychotic, modulates the activity of dopamine and serotonin receptors, helping to alleviate psychotic symptoms such as hallucinations, delusions, and mood disturbances. The combination of these agents provides a synergistic effect, addressing both the depressive and psychotic components of the disorder. Olay Plus is indicated for patients who have not responded adequately to antidepressant therapy alone. It should be administered under strict medical supervision, with dosage adjustments based on clinical response and tolerability. Common side effects may include weight gain, sedation, dry mouth, dizziness, and gastrointestinal disturbances. Caution is advised in patients with a history of cardiovascular disease, diabetes, or seizures. Regular monitoring of metabolic parameters and mental status is recommended during treatment. Olay Plus should not be discontinued abruptly to avoid withdrawal symptoms.
How to use Olay Plus Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Olay Plus Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Olay Plus Tablet.
High Risk
Olay Plus Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Olay Plus Tablet may cause side effects which could affect your ability to drive.
Exercise Caution
Olay Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Olay Plus Tablet may be needed. Please consult your doctor.
Regular Checkup
Olay Plus Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Olay Plus Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Olay Plus Tablet may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Olay Plus Tablet













