Nuromark-PNT Tablet SR
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1 units • OtherPrescription requiredSchedule H
Nuromark-PNT Tablet SR
Pregabalin (75mg) + Nortriptyline (10mg) + Methylcobalamin (1500mcg)
₹210.00
1 units • Other
A valid prescription is required for this medicine.
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Active composition
Methylcobalamin 1500 mcg
+2 more active ingredients
How It Works
Methylcobalamin acts as a cofactor in the synthesis of methionine from homocysteine, promoting nerve health and red blood cell formation.
Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Nortriptyline inhibits the reuptake of norepinephrine and serotonin, increasing their levels in the synaptic cleft and enhancing mood.
Medicine Strength
1500 mcg
All Active Ingredients
Methylcobalamin1500 mcg
Pregabalin75 mg
Nortriptyline10 mg
Uses & Benefits
Medical applications
Pain Relief
Nuromark-PNT Tablet SR is a sustained-release formulation combining Pregabalin 75 mg, Nortriptyline 10 mg, and Methylcobalamin 1500 mcg, designed for the management of neuropathic pain and associated conditions. Pregabalin, an anticonvulsant and analgesic agent, modulates calcium channel function to reduce neurotransmitter release, thereby alleviating neuropathic pain symptoms.
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Nortriptyline, a tricyclic antidepressant, enhances noradrenergic and serotonergic neurotransmission, contributing to pain relief and mood stabilization. Methylcobalamin, an active form of vitamin B12, supports nerve regeneration and repair, promoting neural health and functional recovery. The sustained-release mechanism ensures a gradual and prolonged therapeutic effect, improving patient compliance and minimizing peak-related side effects.
Nuromark-PNT is indicated for diabetic neuropathy, postherpetic neuralgia, peripheral neuropathies, and other chronic neuropathic pain syndromes. It should be used under medical supervision, with dosage adjustments based on clinical response and tolerability. Common adverse effects may include dizziness, somnolence, dry mouth, and gastrointestinal disturbances. Caution is advised in patients with renal impairment, cardiac conditions, or a history of seizures.
Nuromark-PNT Tablet SR offers a multimodal approach to neuropathic pain management, combining analgesic, antidepressant, and neurotrophic effects in a single, convenient dosage form.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Nuromark-PNT Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Pregnancy
Nuromark-PNT Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Driving
Nuromark-PNT Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Nuromark-PNT Tablet SR may be needed. Please consult your doctor.
Exercise Caution
Breastfeeding
Nuromark-PNT Tablet SR may cause side effects which could affect your ability to drive. As Nuromark-PNT Tablet SR may affect your alertness which may affect your ability to drive.
Consult Doctor
Kidney
Nuromark-PNT Tablet SR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Nuromark-PNT Tablet SR may not be needed in these patients. Please consult your doctor.
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