
Nortriptyline (10mg) + Pregabalin (75mg)
Active composition
+1 more active ingredient
Nortriptyline inhibits the reuptake of norepinephrine and serotonin, increasing their levels in the synaptic cleft and enhancing mood.
Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Medical applications
Nuromark-NT Tablet SR is a sustained-release formulation combining Pregabalin 75 mg and Nortriptyline 10 mg, designed for the management of neuropathic pain and related conditions. Pregabalin, an anticonvulsant and analgesic agent, modulates calcium channels to reduce neurotransmitter release, thereby alleviating neuropathic pain symptoms such as burning, shooting, or stabbing sensations. Nortriptyline, a tricyclic antidepressant, enhances noradrenergic and serotonergic neurotransmission by inhibiting the reuptake of norepinephrine and serotonin, contributing to pain relief and improving mood disturbances often associated with chronic pain. The sustained-release mechanism ensures a steady plasma concentration, improving patient compliance and minimizing peak-related adverse effects. Nuromark-NT is indicated for peripheral and central neuropathic pain, diabetic neuropathy, postherpetic neuralgia, and other chronic pain syndromes where combination therapy is warranted. It should be used under medical supervision, with dose adjustments based on clinical response and tolerability. Common side effects may include dizziness, somnolence, dry mouth, and gastrointestinal disturbances. Caution is advised in patients with renal impairment, cardiovascular disease, or a history of seizures. Nuromark-NT Tablet SR offers a synergistic approach to neuropathic pain management, combining analgesic and antidepressant properties in a convenient dosing regimen.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Nuromark-NT Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Nuromark-NT Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Nuromark-NT Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Nuromark-NT Tablet SR may be needed. Please consult your doctor.
Exercise Caution
Nuromark-NT Tablet SR may cause side effects which could affect your ability to drive. As Nuromark-NT Tablet SR may affect your alertness which may affect your ability to drive.
Consult Doctor
Nuromark-NT Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Nuromark-NT Tablet SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Nuromark-NT Tablet SR

Pregabalin (75mg) + Nortriptyline (10mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Nortriptyline inhibits the reuptake of norepinephrine and serotonin, increasing their levels in the synaptic cleft and enhancing mood.
Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Medical applications
Nuromark-NT Tablet SR is a sustained-release formulation combining Pregabalin 75 mg and Nortriptyline 10 mg, designed for the management of neuropathic pain and related conditions. Pregabalin, an anticonvulsant and analgesic agent, modulates calcium channels to reduce neurotransmitter release, thereby alleviating neuropathic pain symptoms such as burning, shooting, or stabbing sensations. Nortriptyline, a tricyclic antidepressant, enhances noradrenergic and serotonergic neurotransmission by inhibiting the reuptake of norepinephrine and serotonin, contributing to pain relief and improving mood disturbances often associated with chronic pain. The sustained-release mechanism ensures a steady plasma concentration, improving patient compliance and minimizing peak-related adverse effects. Nuromark-NT is indicated for peripheral and central neuropathic pain, diabetic neuropathy, postherpetic neuralgia, and other chronic pain syndromes where combination therapy is warranted. It should be used under medical supervision, with dose adjustments based on clinical response and tolerability. Common side effects may include dizziness, somnolence, dry mouth, and gastrointestinal disturbances. Caution is advised in patients with renal impairment, cardiovascular disease, or a history of seizures. Nuromark-NT Tablet SR offers a synergistic approach to neuropathic pain management, combining analgesic and antidepressant properties in a convenient dosing regimen.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Nuromark-NT Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Nuromark-NT Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Nuromark-NT Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Nuromark-NT Tablet SR may be needed. Please consult your doctor.
Exercise Caution
Nuromark-NT Tablet SR may cause side effects which could affect your ability to drive. As Nuromark-NT Tablet SR may affect your alertness which may affect your ability to drive.
Consult Doctor
Nuromark-NT Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Nuromark-NT Tablet SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Nuromark-NT Tablet SR















