
Pantoprazole (20mg) + Domperidone (10mg)
Active composition
+1 more active ingredient
Pantoprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, leading to decreased gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Nupenta-D Capsule is a combination pharmaceutical formulation containing Domperidone 10 mg and Pantoprazole 20 mg, designed for the management of gastrointestinal disorders characterized by acid reflux, dyspepsia, and delayed gastric emptying. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility by increasing the tone of the lower esophageal sphincter and accelerating gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Pantoprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, providing effective relief from acid-related conditions including gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcer disease. The combined action of these agents offers symptomatic relief and promotes mucosal healing. Nupenta-D is indicated for patients with symptomatic GERD accompanied by delayed gastric emptying or upper gastrointestinal motility disorders. It should be administered as prescribed by a healthcare professional, with consideration of contraindications such as hypersensitivity to either component, prolactin-dependent tumors, or concurrent use of medications that prolong the QT interval. Monitoring for adverse effects like headache, dry mouth, or abdominal cramps is recommended. This combination therapy optimizes patient outcomes by addressing both acid suppression and motility enhancement in gastrointestinal management.
How to use Nupenta-D Capsule Take this medicine in the dose and duration as advised by your doctor. Nupenta-D Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Nupenta-D Capsule. Please consult your doctor.
High Risk
Nupenta-D Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Nupenta-D Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Nupenta-D Capsule is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Nupenta-D Capsule may not be needed in these patients. Please consult your doctor.
Regular Checkup
Nupenta-D Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Consult Doctor
Nupenta-D Capsule should be used with caution in patients with kidney disease. Dose adjustment of Nupenta-D Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Nupenta-D Capsule

Domperidone (10mg) + Pantoprazole (20mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Pantoprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, leading to decreased gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Nupenta-D Capsule is a combination pharmaceutical formulation containing Domperidone 10 mg and Pantoprazole 20 mg, designed for the management of gastrointestinal disorders characterized by acid reflux, dyspepsia, and delayed gastric emptying. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility by increasing the tone of the lower esophageal sphincter and accelerating gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Pantoprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, providing effective relief from acid-related conditions including gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcer disease. The combined action of these agents offers symptomatic relief and promotes mucosal healing. Nupenta-D is indicated for patients with symptomatic GERD accompanied by delayed gastric emptying or upper gastrointestinal motility disorders. It should be administered as prescribed by a healthcare professional, with consideration of contraindications such as hypersensitivity to either component, prolactin-dependent tumors, or concurrent use of medications that prolong the QT interval. Monitoring for adverse effects like headache, dry mouth, or abdominal cramps is recommended. This combination therapy optimizes patient outcomes by addressing both acid suppression and motility enhancement in gastrointestinal management.
How to use Nupenta-D Capsule Take this medicine in the dose and duration as advised by your doctor. Nupenta-D Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Nupenta-D Capsule. Please consult your doctor.
High Risk
Nupenta-D Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Nupenta-D Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Nupenta-D Capsule is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Nupenta-D Capsule may not be needed in these patients. Please consult your doctor.
Regular Checkup
Nupenta-D Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Consult Doctor
Nupenta-D Capsule should be used with caution in patients with kidney disease. Dose adjustment of Nupenta-D Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Nupenta-D Capsule















